I was looking over some of the protocals that Dr. Murphree advertises, and one of the things he said was that he recommends his patients to take 300MG of 5HTP. I was slightly confused by that, because the 5HTP that I have is 50mg per capsule, and the bottle says take one. So.. does anyone have any input on how they take 5HTP? And is it helpful to you? Also, my bottle says not to take it within 2 hours of taking medications, because it can change their effects. This would be difficult to do at night (when I think its supposed to be taken) since I take meds for sleep.