Greetings to all the wonderful folks on this board: My adult daughter has this challenging illness and I am wondering what folks think is a safe and realistic level of activity for someone who was functioning at about 6.5---8/10. You see, she had a relapse in Oct and is still not out of it. She became ill in May 2002 following infection after surgery; she was bedridden for months and years and then by March 2006 functioned at around 6.5-7/10 and went to work part=time as a junior attorney. She crashed after working for 9 months in Nov. of 2006 and had this first relapse until the end of the summer of 2007, at which point she was improved again. We concluded that this work arrangement was the culprit. Fine, so when she got better, we decided a more restrained lifestyle would be better. She registered for a graduate degree and was taking it half-time, which meant one course per semester; students met only once a week and the rest of the time she was at home reading and doing the research from home. She loved the work and our plan was to prevent a relapse. Bang, on Oct. 5th 2008, some 14 months after what was a relatively normal life, she had a major relapse. We remain bewildered. She was not on a job; she could lie-in if needed; she could postpone research if needed; she had the one commitment to the class and if that wasn't feasible she could follow it on the internet. Housework was not an issue. She went to a 2 and a half day seminar--a one time event and crashed after it. She had gone to one day conferences before with no nefarious effect. So, my question is how in the heck does one prevent a horric relapse. What level of activity is dangerous? She is utterly devastated by this. And has starting worrying that life must be circumscribed to just sitting in the house like a cat and not doing much. Please recall, her level was prior to Oct 2008 around 7.5-8/10 with some moments of what she called 'normal' feeling, for the first time since becoming ill. The crash gave no warning whatsoever that it was coming; no warning, just Bang, adrenal collapse, and severe. She just felt that something went 'pop' inside of her, as she put it. The physician is wondering if she doesn't have lyme or neurotoxins now, but there was no bite and the question is: why would she get to such a good functioning level if there was lyme and neurotoxins. If anyone out there has any advice, speculations or observations, I will be eager to hear. For instance, what kind of exercise is acceptable: riding a bike? swimming? are these dangerous? light weight lifting? You see, the botton line is: even after getting better, is it possible to resume anything resembling even a partial normal life. Thanks for reading this. Time is our most precious possession after good health.