I recently got back in touch with a childhood friend on Facebook. I haven't seen her since we were about 16 or 17 and we're 45 now. After catching up on spouses/partners/kids/pets, we started talking about illness. She told me that she'd had Fibro/CFS, which shocked me because she now has a toddler (oh man, just taking care of pets is enough for me - I couldn't imagine being responsible for an endless ball of energy 24/7) and seems to be doing just fine. So, I asked her what helped her. I'm going to quote her because I haven't tried these supplements yet. I can barely afford food right now, and even then, it's with the help of my parents. So, unfortunately, I'm afraid to spend extra money on something that may not help me. I'm hoping that maybe with the next Amazon g/c I earn, I'll be able to buy a couple months' worth. Anywho, take this for what it's worth to you. She says that she now feels 95% normal and that when she's tired, she's not sure if it's the FM or if it's just being the mom of a toddler. I'm guessing that if she's not sure, then it's probably just regular ol' mom tiredness. FM/CFS fatigue is pretty all-encompassing usually and the only thing most people would mistake it for would be the flu or mono, or something like that. "I took the Enada (NADH) 2 times per day on an empty stomach at least 1/2 hour before eating. I took the magnesium 2x per day with meals. I think they both helped a lot...I would say the Magnesium helped my pain and the Enada REALLY helped my energy. I also took a multi-vit and A LOT of other things (at one point taking 18 supplements a day) like coQ-10 (really expensive) and other things...but I felt the mag and Enada were both something I could "feel" helped...never felt anything else did much good." So, here is what helped a friend. It won't cost you your life's savings and I even think PH sells everything, so I'm totally on-topic and not questioning anyone else's magical cure. I'm sure some of you have tried this exact combination of supplements - did it help you? I know that I've felt better since I started drinking more grapefruit juice (it also helps my pain meds go further as a potentiator, plus the Simply Juice brand of white gf juice actually tastes good, unlike the Ocean Spray stuff that tastes skunky, blech) and that would be more magnesium than I normally get. Maybe if I just add the NADH, I'll feel better.