Hi! I'm 34 yrs old and have been struggling with severe symptoms of adrenal fatigue for 15 years. I recently found a great MD who specializes in adrenal dysfunction, and after hearing my history and symptoms, he had no doubt that a salivary cortisol test would confirm what we both felt was a severe case of adrenal fatigue. Well, guess what? The tests came back normal. He was shocked, and said that it's been 5 years since he's seen anyone like me who has a perfect clinical profile of adrenal fatigue, but has normal test results. He said that it might be possible that I'm someone who needs higher than "normal" cortisol levels to feel normal. He asked me to start taking 2.5 mg Cortef to see how my body responds to the extra cortisol. So, I have several questions. Is it possible to have "normal" salivary cortisol levels, but still have adrenal fatigue? How soon should I notice the effects of the Cortef? I am desperately hoping that this will make a difference.