PDR means "Physicians Desk Reference" and is used by doctors to look up meds, toxins and conditions. http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/alp_0159.shtml Alpha Lipoic acid has a half-life of 3 hours...so especially for chelation, take a smaller amount: 25mg or 50mg every 3 hours, 3 days ON, 3 days OFF. Synthetic drug chelators (DMSA & EDTA) remove toxins and metals from outside the cells (extra celluar) but ALA remove them intra-celluar and even crosses the blood-brain-barrier. "Lipoic acid's role in immunity is not well understood. There are reports that it can augment antibody response in some animal models of immunosuppression. This research warrants followup." "In some animal experiments, lipoic acid, administered for up to three months, significantly reversed the increase in nerve vascular resistance and the decrease in nerve blood flow in diabetic rats. Nerve conduction velocity was entirely restored in some nerve groups after three months of treatment." Viruses breathe glucose (sugar) so keeping it at an ideal lower level is vitally important. ALA is made by the human body and its a natural product but taking larger amounts of it certainly has benefits.