My fibro pain has been increasing for some time. I have searched my brain to figure out why I feel so awful. The doctor put me on Evista for osteoporosis about four years ago. Now I am doing without it for a week to see if it is part of the pain cycle. But I am also suspicious of the Splenda that I have been using for several years. Does anyone have any experience with Splenda? Is there any connection between it and pain? Frankly, after decades with fibromyalgia, I am getting close to despair. This is such a hard disease to treat. Because of sensitivity to medication I am basically on my own, and the unremitting pain is a huge downer!