Amino Acids (neurotransmitters) Treatment of CFS /FMS ....

Discussion in 'Fibromyalgia Main Forum' started by elsa, Sep 15, 2005.

  1. elsa

    elsa New Member

    I was researching more information this morning on the amino acid l-cysteine as it was suggested by ND that I take it while on mucana prurien (for dopamine production) for balance.

    I found alot of information on other amino acids that I thought could be helpful. I'm not suggesting anyone run out and buy it all, but perhaps give them some research of your own.

    Some listed I have experience with or are taking presently for CFS/FM.

    Take care,


    ARGININE .. Insulin production, muscle metabolism, liver lipid metabolism, component of collogen, enhances immune system ( specifically by stimulating thymus gland and manufacture of t-cells), maintain nitrogin balance in muscles and enhance lean tissue to fat tissue body fat ratio.

    The increase of t-cells activity can be effective in fighting bacteria, viruses, cancer tumer cells, chronic fatigue synd..

    It neutralizes ammonia and helps in liver detoxification and regeneration.

    As a component of collogen, assist in wound healing, skin problems, arthritis and connective tissue problems.

    ASPARTIC ACID ... aids in expulsion of ammonia from circulation system. Ammonia is toxic to CNS and can cause neural and brain disorders.

    CARNITINE ...Transfer fat from fat cells to mitochondria to be burned for energy.

    Body makes it's own supply, but the manufacture process requires b1,b6,vitc, lysine and methionine. If any of these are inadequate, manufacture will not take place.

    CYSTEINE ... collogen production skin elasticity and texture. Alpha kerotin in nails and hair. Cysteine makes up 10-14% of hair and skin. Helpful when dealing with burns, surgery recovery and rheumatoid arthritis.

    Cysteine is a powerful free radical destroyer and works best with vit E and selenium in this capacity. Involved in breakdown of mucus in lungs.

    GLUTAMIC ACID .... Precurser to Gaba but somewhat opposite function. It is an excitatory neurotransmitter and one of the few that cross the blood brain barrier. It is the only means in which ammonia in brain can be detoxified.

    It is considered to be nature's "brain food" by improving mental capacities. Used in treatment of ADD, ADHD, depression, CFS, epilespsy, etc..

    GLUTAMINE ... Readily passes blood brain barrier. Increases Gaba and Glutamic Acid. Enhances normal CNS function. During times of stress, illness or surgery, up to 1/3 of muscle stores of glutamine are released for nervous system usage causing extensive muscle deterioration and loss. Muscle released glutamine occures at a much lower rate when supplemental l-glut. is used.

    HISTIDINE ... Found in red and white blood cells. Component of myelin sheaths that protect nerve cells. Used in treatment of arthritis, allergies and ulcers.

    HistaMINE is derived from hisidine. Involved in immune system and sexual response. Needs b3 and b6 to convert to histamine.

    ISOLEUCINE ... one of three branched chain amino acids ( leucine, valine). Enhances energy, increase endurance, aid in muscle tissue recovery and repair.

    This group lowers elevated blood sugar levels and increases growth hormone production. Should always be combined with leucine and valine at ratio of 1:2:2.

    METHIONINE ... Sulfer, inactivates free radicals, produces lecithin, reduces fat in liver and protects kidneys.
    *** Natural chalating agents - heavy metals.

    ORITHINE ... participates in release of growth hormone, prompts metabolism of excess body fat. Enhanced by presence of arginine and carnitine.

    PHENYLALANINE ... In brain to produce dopamine and norepiniphrine which are chemicals that promote alertness, elevated mood, and decrease of pain. Also aids in memory and learning and reduces hunger and appetite.

    TYROSINE ... Helps promote healthy function of thyroid, adrenal and pituitary glands. Suppresses appetite and helps reduce body fat. Research shows helps in treatment of narcolepsy, CFS, depression , allergies, headaches and parkinson's disease.

    From Dr. Steven Whiting ( Institute of Nutritional Science)

    "All or None Law of Protein Utilization"

    If all are not present within a 2 to 3 hour window period, then protein assimilation will not work.

    Even when all are present, assimilation of all amino acids will be limited to the level of the lowest quantity of amino acid. For example, If one amino acid is present at the 60% level, the assimilation of all amino acids will be limited to that 60% level.

    [This Message was Edited on 01/21/2006]
    [This Message was Edited on 01/21/2006]
  2. tandy

    tandy New Member

    I do take a mega multi vitamin and it has small amounts of some of these aminos listed.
    I've read before that some of the ones listed here are suppose to be very good for us~
    Swanson has really good prices on their supplments.
    Thanks for sharing this with us :)
  3. laura81655

    laura81655 New Member

    I take L-Cysteine, and Phenylalanine. One of my doctor's told me about amino acids to use for neurotransmitter dysfunction. The site is The site is confusing, but I like the idea of using amino acids to help with pain instead of meds.
    Thanks for sharing this.
  4. elliespad

    elliespad Member

    I have worked with Dr. Dennis Gersten in Solona Beach, California. Also goes by David Gersten. (I live in New York) He is very big on Amino Acids and natural supplements. He has several websites, one of which deals with amino acids at, aminoacidpower dot com.

    I had MANY tests done that my regular MDs and specialists never heard of. Like, Amino Acid Profile, Oxidative Stress, Cellular Energy Profile, things that looked at Mitochondrial funciton. You name it, he tested for it. Bright guy. Hmmmm. Need to get back with him. Anyway,,, you might enjoy his website.
  5. elsa

    elsa New Member

    I will look into it. I got involved with amino acid therapy in a round about way.

    What did I want? I wanted my energy back. How do you want to feel emotionally? Happy, energized and up beat.Then find a way to get it done.

    At the moment, my doctor and I are working on the happy, energetic, functioning brain side of things. Early going, but definate signs of improvement.

    As I balance the serotonin with elevating dopamine, I am using less pain medication. I've been sitting here this am wondering how come the pain hasn't hit? Why don't I need to run to the pill bottle? It's a nice feeling and one I hope lasts.

    I am addressing the more physical aspects of fatigue with a hormone specialist ... not a traditional endo.. There is no way I could feel like this and have beautifully balanced hormones. LOL Once that goal is accomplished, I'd like to continue with amino acid therapy beyond brain chemicals.

    Thank you for listing the information. I do indeed look forward to learning more.


  6. elsa

    elsa New Member

    I hope this finds it way back to the top. I just re-read it and reminded myself that some new members may like to check it out.

  7. elsa

    elsa New Member

    Someone asked about this ... bumping back to top ... Thanks

    ANNXYZ New Member

    bump for those with questions about dopamine .
  9. Tantallon

    Tantallon New Member

    This is really good info Elsa, thank you.
  10. WendyC

    WendyC New Member

    This is a supplement that I take with a lot of amino acids. I just ran out and boy do I feel terrible. I am waiting for the reorder to arrive. This supplement is absolutely essential for my health.

  11. Roseblossom

    Roseblossom Member

    I am such a fan of them - they have helped me so much!

    Anyone interested in how much they can help us should type Amino Acids into the Search bar above, and read all the positive comments.

    Thanks, Elsa & all!

  12. ANNXYZ

    ANNXYZ New Member

    What brand of aminos do you take ? How have they helped you with your symptoms?
  13. Roseblossom

    Roseblossom Member

    I have CFS, and these amino acids are the best thing I've felt making a difference, along with sublingual vitamin B.

    I'm going to try Elsa's chewable wafer with all the amino types in it, too. I've read about the one that calms all the noise in the brain too, do you remember which one that is?

    I learned about my amino acids from my sister who uses them, research on the internet, and from a book called The Mood Cure, by Judith Ross.

    First thing in the morning after a glass of pure water I take a capsule of a blend of amino acids called Neuro Optimizer made by Yarrow - gets rid of brain fog and gives me energy & optimism.

    Most days after breakfast I take one L-Tyrosine, which increases dopamine - good for feeling enthusiasm for life again.

    After dinner I'll occasionally take one 5HTP which increases seratonin - helps calm me when I feel cranky or anxious or have been sleeping poorly. Must take this one with food to avoid nausea.

    These have really helped me in my miserable journey to wean off of Effexor, which was making me feel sicker. It's taken months, but I'm down to only 37 mgs now, and I feel much better :)

    Which ones are working best for you, Ann?

  14. Roseblossom

    Roseblossom Member

    From fatigued to fantastic' is the name of the supplement? What's it like?

  15. ANNXYZ

    ANNXYZ New Member

    is N acetyl cysteine , which is a precursor ( esp if taken with selenium) to GLUTATHIONE . I feel it is THE MOST IMPORTANT SUPPLEMENT I TAKE . Glutathione is the body's NUMBER one detoxifier ( goes after bacteria , viruses, toxins ) and is made in the liver . Good health is impossible without it . My doc , who is healthy takes it daily .

    I quit taking it during a time i was moving across country , and became ill within two weeks with severe chest infection. I will never do that again. Even though I have lyme , I think the N A C really keeps me from having other infections . I rarely get sick with the infections that everyone around me gets.

    I am definitely ordering some amino acids , and will try some tyrosine with B6 ( I think twinlab makes a combo ) to see if this helps with mood . I am curious about phenylaniline which is a precursor to dopamine .
    I would like to see if these help with mood and concentration. From what I read , the VIT B 6 HAS TO BE PRESENT with some of these to work. Also , VIT B 6 is
    vital to brain health . ( I read about it several places - one was medline plus . ) It seems the B vit's and the amino acids have a strong effect on mood .
  16. ANNXYZ

    ANNXYZ New Member

    I may try the Jarrow neuro optimizer and the tyrosine with Vit B6 .

    I think the wafers are predigested and by NOW .

    If you google " The Way Up From Down " ( a book about treating depression and anxiety with aminos ) you will find a webpage with useful info about the helpfulness of aminos with mood and also mentions pain , I believe .

    It is easy to read and interesting .
  17. WendyC

    WendyC New Member

    is a supplement developed by Dr. Teitlebaum who is a major researcher and doctor for FM and CFS (you can search the library here). It is a powder which I mix with water and take around noon. I love it. You can buy it here or Vitasource. 27-34 dollars for a months supply. Lots of vitamins, amino acids, check out label information at the store and it will list all ingredients. Good luck

  18. Roseblossom

    Roseblossom Member

    Hey Ann, I really like all the health information included in the Way Up From Down site. I'm exploring this some more - very smart doctor.! Ann, check out this supplement powder that Wendy recommended - I just finished reading about it here on ProHealth. Fatigued to Fantastic. I'm going to try it :)

    It has the amino acids, including your N-Acetylcysteine (NAC) 250 mg, and Tyrosine, plus the Bs and other vitamins & minerals.

    And it has tons of other stuff in it that I've been wanting to try. This may be able to replace many of my other supplements all in one.

    I'm going to purchase it from ProHealth because they sponsor our forum here :)

    Thanks, Wendy :) One question - can you take it on an empty stomach even with the tryptophan? Or is it better to take with a meal.

    Thanks to everyone who has shared on this thread!


  19. WendyC

    WendyC New Member

    because my digestive track is such a mess. I am adding digestive enzymes and probiotics to try and deal with my 'issues'. I will start taking a prescription for nystatin for yeast soon. I think it would be fine to take the drink with or without food. I too am trying to find supplements that combine as much as possible, otherwise you end up taking 20-30 supplements a day.

  20. Roseblossom

    Roseblossom Member

    That's good to hear, because when I first get up I need that infusion of energy, and I'm unable to eat anything until I've been awake for awhile - I only drink pure water and then my beloved fresh-ground coffee :)

    I can't wait to try this - if I feel good on it it'll replace some of my current vitamin/mineral/amino supplements, and that will simplify my little life.

    Hooray for simplicity and serenity :)


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