Ankles and knees just throb. At night it is horrible for my ankles...especially the backs of them and up a little on the side of the calf. Now, even in the days my ankles and knees just throb. They feel like they have been broken a month ago and are that weak also. One year ago I was given a 7 day dose of a super powerful antibiotic called Levaquin. That first day or two I was on this is when all my present symptoms began. And they have gotten progressively worse since then. My wrist and shoulders hurt like heck all the time too. But my ankles and knees...oh man...feel like I might have to use a walker eventually. Unbelievable. Was fine up until one year ago! Any suggestions for relieving the pain in these areas?