I have has CFIDS for five years now. I think I have tried about every antideprssant that exists with the hopes that I would get an added boost of energy from them. My problem is that every thing I try causes me to have severe insomnia. My latest trial was with Lexapro. It seems like whatever goes up must come down. I have tried Ambien and Klonopin for the insomnia, but the antidepressants seem to override and stay in my system for a long time and can lead to a relapse. Has anyone tried combining the SSRI antideprssants with a tricylics. I am not sure how safe this may be. Anyone that has information that might help and I can share with my doctor would be helpful. I have also tried Neurontin to no avail.