I am currently looking to change from my natural supplements (St. John's Wort and 5 HTP)to an RX medication that may help me better. I suffer from unexpected anxiety and panic attacks and they are more bothersome than my fibro pain at the moment. I have been putting off going on an anti-depressant as I have heard so much bad feedback about alot of them. I am currently taking Xanex 3 times a day for my anxiety but am afraid that I am building an tolerance to it and will have to keep taking more and it is addictive. Also, has anyone tried SAM-E? I heard that it could be taken in addition to anti-depressants. Any suggestions of what has helped others would be appreciated. Thanks.