I've got a teen son on the spectrum & am interested in the Yasko protocols ... highly technical as they are. Seems like most who are doing the autism protocol are getting the genetic SNP tests done first, so that they can target the nutritionals. I'm just wondering whether anyone here has done one of the SNP test panels -- or if anyone knows what the most common glitches are, specifically in CFS/fibro -- beyond the general "methylation path is affected." Regarding cheap copies of Yasko's book -- I'm not sure which title you are referring to, but I've put in requests for several of her books through public library interlibrary loan. ILL in my town costs $1 plus postage, usually around $2.50 total. Not a bad deal if one is a speedy reader & note-taker. Best wishes.