Just wondering. I have a bottle of them, 200mgs each by Nature's Rx, they have b-12 and folic acid in them also, and curcumin Has it helped? and if so, what did it help with? Any negative reports also. Very curious. I just took 1 tab and have heart burn. Many patients ask me about this and St John's wort. All I know is the interaction that St. Johns Wort causes with certain meds.