...reaction than it had for years? I have been on Paxil for probably 14 years now. It was originally prescribed for panic attack disorder which started when I was 19 and in college and scared to death. I wish I had never started it. But I was desperate. It's weird that an AD can sometimes help with panic because they are actually stimulants. It did seem to help me for years, but over the past year or so, and ESPECIALLY since my horrific Effexor trial and withdrawal incident, it is VERY stimulating to me and making my panic/anxiety worse. I think this was starting to be it's effect even before the Effexor, but now everything is much worse. Now I am trying to very slowly taper off the Paxil and see if it helps. I am going super slow, so that I don't go through another horrible withdrawal like with the Effexor (probably still feeling the effects of that). My rheumy called me in the liquid form of Paxil so I can go down by 1 mg at a time. I'm also moving it up in the daytime to where I take it. I've always taken it at night which is weird too, I guess. No one ever told me I should take it in the morning. Does anyone have any experience that could shed some light on all this? Thank you!