I've been taking cortisol for about 1 1/2 yrs. and found out recently that the 50 pds I've gained in the last year is from the cortisol. the doctor said it should be reduced. but I've cannot afford to go to him anymore. I know cortisol is important for the function of the adrenals which I have low functioning. but I was so depressed that I stopped taking them. my regular doctor said to be careful taking them and to go online and check out the safety of cortisol. I look like I am 9 months pregnant. and this is where they said you would gain it, in your belly. is there anyone out there that has a similar experience?