Below is a desription of it. A woman from my work thought I might have this. Any thoughts? Reflex sympathetic dystrophy (RSD) is a complex, poorly understood disorder that is characterized by chronic, severe pain and progressive changes in skin, muscle, and bone. Although the precise causes of RSD are unknown, it often occurs following an injury, often minor in nature. Some experts believe that RSD represents an exaggerated response of the sympathetic nervous system to some form of injury or insult (eg. surgery) to the area resulting in chronic, severe, sometimes debilitating pain.