anyone, question on simplified & meds and vitamns

Discussion in 'Fibromyalgia Main Forum' started by simonedb, Jul 2, 2008.

  1. simonedb

    simonedb Member

    I am leaning towards trying to do the simplified approach,
    are there any meds or vitamins you discourage or think could be counterproductive with simplified? For ex i like to take d3 and I was considering taking a good MVI, was rec'd the nutrient 950 but then i saw it has that riskier form of vitamn b and I dont know if I should be taking that cus have p450 issues, but I don't know what polymorphisms specifically but I do know I seem to herx even on the good type of b if I do an injection that isnt miniscule.

    also any experience w/ trying the LDN along with simplifed approach?
    I'm already doing every now and then csf (can't tolerate a lot or often), but the LDN sounds too intriguing to ignore.

    [This Message was Edited on 07/03/2008]
  2. Diva55

    Diva55 New Member

    You might want to post this question on the Yasko CFS_Yahoo group where people are doing the longer Yasko protocol as well as Rich's Simplified Protocol.

    I know you should avoid additional forms of folic acid. I don't know anything about the other things you are asking about.

    You should consult your doctor regarding any meds and interaction with Rich's 5 basic supps. Better still take Rich's paper to the doctor.

    Best wishes
  3. richvank

    richvank New Member

    Hi, simonedb.

    Here are some excerpts about that from the update I posted on July 18, 2007. I think they are still current:

    "I am not aware of negative interactions between the five basic supplements and prescription medications used by physicians in treating CFS. However, this treatment approach should not be attempted without considering together with a licensed physician possible interactions between the supplements included in it and any prescription medications that are being taken. This is particularly important if addition of SAMe to the basic five supplements is contemplated."

    "When this treatment approach is used together with prescription medications, a licensed physician must be consulted before discontinuing any prescription medications. Some of them can cause very serious withdrawal symptoms if stopped too abruptly."

    "If this treatment approach is begun by a PWC who is taking a thyroid hormone supplement for a hypothyroid condition, the PWC and the supervising physician should be alert to the possibility that HYPERthyroid symptoms, such as palpitations and sweats, can occur, even very soon after starting this treatment. The physician should be consulted about possibly adjusting or eliminating the thyroid hormone supplementation if this occurs."


    "With regard to possible interactions between the supplements in the simplified treatment approach and other supplements that PWCs may be taking, I am aware of two: (1) I would not recommend taking additional folate beyond what is suggested above, since the various forms of folate compete with each other for absorption, and it is important to get enough of the active forms into the body. Also, it is important not to take too much folate, as mentioned above, because this can cause the detox to develop a momentum, so that it will take some time to slow it down if you want to do that. (2) I would also not recommend taking additional trimethylglycine (TMG, also called betaine) or additional forms of choline, such as phosphatidylcholine or lecithin, since that may stimulate the BHMT pathway too much at the expense of the methionine synthase pathway. The betaine-HCl used to augment stomach acid is something that may have to be omitted while doing this treatment, too, since it will contribute to this stimulation."

    "Adding glutathione support will help some people, as will adding molybdenum.
    As more things are added, though, one is moving toward the full Yasko approach, which is more complicated and expensive. If this is done, I recommend that it be done with the guidance of Dr. Yasko and under the supervision of a personal physician. The simplified treatment approach appears to work well by itself for many PWCs, but others may find that the die-off and detox (or even adverse effects) from this approach used by itself are too severe. In those cases, the PWCs could consult “The Puzzle of Autism,” sold on, to consider together with their doctors what else discussed there might help them. If the simplified approach seems to help to some degree, and it captures one’s attention for that reason, but it still either does not accomplish all that is desired, or it is not tolerated, then perhaps the next step would be to consider the full Yasko treatment. At least then there would be stronger motivation to look into it. Otherwise, it can appear very daunting to many PWCs."