I was reading my email today, and this article was there. Thought it might be helpful. Action Potential Simulation Ineffective in Fibromyalgia Patients According to researchers at the Rudolf Magnus Institute of Neuroscience, The Netherlands, an increasingly popular method of pain reduction did not have any affect on the 10 fibromyalgia patients they studied (Clinical Rheumatology, 2007 Mar;26(3):322-9). Action potential simulation (APS) is a form of microcurrent electrical stimulation which is hypothesized by its proponents to works by stimulating neurons which may replenish the cell's pain energy source (ATP). It has not been widely researched for the treatment of pain but is similar in many ways to the commonly used TENS (Transcutaneous Electrical Nerve Stimulation) unit. The study aimed to investigate "whether APS helps to reduce pain, improves patients' perception of daily functioning and social participation in patients with fibromyalgia syndrome (FMS)." The patients were treated twice with APS, for four weeks each time. One of the four-week sessions was with APS and another with a placebo. The researchers measured their outcomes weekly, primarily focusing on their pain levels and tender points. No positive results of the APS treatment were found. It did not reduce pain or improve patients' perception of their daily functioning. In fact, researchers were surprised to find that the placebo APS had significantly better results than the real APS treatment.