Arthritis and FM: meta050

Discussion in 'Fibromyalgia Main Forum' started by tansy, Nov 5, 2005.

  1. tansy

    tansy New Member

    A Pilot trial evaluating meta050, a proprietary combination of reduced
    iso-alpha acids, rosemary extract and oleanolic acid in patients with
    arthritis and fibromyalgia.

    Phytother Res. 2005 Oct 31;19(10):864-869 [Epub ahead of print]

    Lukaczer D, Darland G, Tripp M, Liska DA, Lerman RH, Schiltz B, Bland JS.

    Clinical Research at the Functional Medicine Research Center, Gig Harbor,
    WA, a division of Metagenics, Inc.

    PMID: 16261517

    The aim of this open-label, 8-week observational trial was to investigate
    the efficacy of Meta050 (a proprietary, standardized combination of reduced
    iso-alpha-acids from hops, rosemary extract and oleanolic acid) on pain in
    patients with rheumatic disease.

    Osteoarthritis, rheumatoid arthritis and fibromyalgia patients were given
    440 mg Meta050 three times a day for 4 weeks, which was changed to 880 mg
    twice a day for the subsequent 4 weeks in the majority of patients. Pain
    and condition-specific symptoms were assessed using a standard visual
    analog scale (VAS), an abridged arthritis impact measurement scale (AIMS2)
    and the fibromyalgia impact questionnaire. Fifty-four subjects with
    rheumatic disease completed the trial.

    Following treatment, a statistically significant decrease in pain of 50%
    and 40% was observed in arthritis subjects using the VAS (p < 0.0001;
    Wilcoxon-ranked sums) and AIMS2 (p < 0.0001), respectively. Fibromyalgia
    subject scores did not significantly improve. A decreasing trend of
    C-reactive protein, a marker for inflammation, was also observed in those
    subjects who presented with elevated C-reactive protein. No serious side
    effects were observed.

    These observations suggest that Meta050 at a dosage of 440 mg three times a
    day has a beneficial effect on pain in arthritis subjects.
  2. fivesue

    fivesue New Member

    anti-inflamatory agent as it helps arthritis but not FM. Interesting, and what I really like is that the medical community is actually putting FM in the same category as other very well recognized diseases. That is really a big improvement.

    Now, if it would only reach down to the local level. Guess all things take time.

    Thanks for posting. Good infe.