Autism Increase NOT Due to better counting, diagnosis

Discussion in 'Fibromyalgia Main Forum' started by mindblower, Jan 11, 2009.

  1. mindblower

    mindblower New Member

    For those following the methylation cycle block-glutathione depletion hypothesis for ME/CFS and recall Rich's theorizing a connection between ME/CFS and autism, you may find this new article of interest. I recall Rich predicting this finding years ago, but I'll let him verify this point or not if he actually did:

    "California's Autism Increase Not Due To Better Counting, Diagnosis

    ScienceDaily (Jan. 11, 2009) — A study by researchers at the UC Davis M.I.N.D. Institute has found that the seven- to eight-fold increase in the number children born in California with autism since 1990 cannot be explained by either changes in how the condition is diagnosed or counted — and the trend shows no sign of abating.

    Published in the January 2009 issue of the journal Epidemiology, results from the study also suggest that research should shift from genetics to the host of chemicals and infectious microbes in the environment that are likely at the root of changes in the neurodevelopment of California's children.

    "It's time to start looking for the environmental culprits responsible for the remarkable increase in the rate of autism in California," said UC Davis M.I.N.D. Institute researcher Irva Hertz-Picciotto, a professor of environmental and occupational health and epidemiology and an internationally respected autism researcher.

    Hertz-Picciotto said that many researchers, state officials and advocacy organizations have viewed the rise in autism's incidence in California with skepticism.

    The incidence of autism by age six in California has increased from fewer than nine in 10,000 for children born in 1990 to more than 44 in 10,000 for children born in 2000. Some have argued that this change could have been due to migration into California of families with autistic children, inclusion of children with milder forms of autism in the counting and earlier ages of diagnosis as consequences of improved surveillance or greater awareness.

    Hertz-Picciotto and her co-author, Lora Delwiche of the UC Davis Department of Public Health Sciences, initiated the study to address these beliefs, analyzing data collected by the state of California Department of Developmental Services (DDS) from 1990 to 2006, as well as the United States Census Bureau and state of California Department of Public Health Office of Vital Records, which compiles and maintains birth statistics.

    Hertz-Picciotto and Delwiche correlated the number of cases of autism reported between 1990 and 2006 with birth records and excluded children not born in California. They used Census Bureau data to calculate the rate of incidence in the population over time and examined the age at diagnosis of all children ages two to 10 years old.

    The methodology eliminated migration as a potential cause of the increase in the number of autism cases. It also revealed that no more than 56 percent of the estimated 600-to-700 percent increase, that is, less than one-tenth of the increased number of reported autism cases, could be attributed to the inclusion of milder cases of autism. Only 24 percent of the increase could be attributed to earlier age at diagnosis.

    "These are fairly small percentages compared to the size of the increase that we've seen in the state," Hertz-Picciotto said.

    Hertz-Picciotto said that the study is a clarion call to researchers and policy makers who have focused attention and money on understanding the genetic components of autism. She said that the rise in cases of autism in California cannot be attributed to the state's increasingly diverse population because the disorder affects ethnic groups at fairly similar rates.

    "Right now, about 10 to 20 times more research dollars are spent on studies of the genetic causes of autism than on environmental ones. We need to even out the funding," Hertz-Picciotto said.

    The study results are also a harbinger of things to come for public-health officials, who should prepare to offer services to the increasing number of children diagnosed with autism in the last decade who are now entering their late teen years, Hertz-Picciotto said.

    "These children are now moving toward adulthood, and a sizeable percentage of them have not developed the life skills that would allow them to live independently," she said.

    The question for the state of California, Hertz-Picciotto said, will become: 'What happens to them when their parents cannot take care of them?'

    "These questions are not going to go away and they are only going to loom larger in the future. Until we know the causes and can eliminate them, we as a society need to provide those treatments and interventions that do seem to help these children adapt. We as scientists need to improve available therapies and create new ones," Hertz-Picciotto said.

    Hertz-Picciotto and her colleagues at the M.I.N.D Institute are currently conducting two large studies aimed at discovering the causes of autism. Hertz-Picciotto is the principal investigator on the CHARGE (Childhood Autism Risk from Genetics and the Environment) and MARBLES (Markers of Autism Risk in Babies-Learning Early Signs) studies.

    CHARGE is the largest epidemiologic study of reliably confirmed cases of autism to date, and the first major investigation of environmental factors and gene-environment interactions in the disorder. MARBLES is a prospective investigation that follows women who already have had one child with autism, beginning early in or even before a subsequent pregnancy, to search for early markers that predict autism in the younger sibling.

    "We're looking at the possible effects of metals, pesticides and infectious agents on neurodevelopment," Hertz-Picciotto said. "If we're going to stop the rise in autism in California, we need to keep these studies going and expand them to the extent possible."

    The study was funded by grants from the National Institute of Environmental Health Sciences (NIEHS) and by the M.I.N.D. Institute.
    Adapted from materials provided by University of California - Davis - Health System.
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    [This Message was Edited on 01/11/2009]
  2. Rafiki

    Rafiki New Member

    studying child development and psychology, we were taught that autism was caused by distant and uncaring mothers. They were referred to as "refrigerator mothers". I believed it.

    No matter how hard we have it, we have an easier time of it than those poor mothers.


  3. spacee

    spacee Member

    I don't compare one person's suffering to another's. There are people here who have suffered far greater than others in their humiliation by doctors, friends, family, etc.

    Please don't say we have an easier time of it. Some do, some don't. Just the way it is.

    Just my thoughts

  4. hermitlady

    hermitlady Member

    Both of my kids have autistic traits. I have just been diagnosed w Mitochondrial Disorder, not a specific type yet.

    Research has found that Autism is one of many problems related to mito disorders. I am still learning about it and have lots of genetic testing ahead of me (which will eventually include my children). I'll bet you anything that there's a link here.

  5. Iamwell

    Iamwell New Member

    Scientists estimate that 90 percent of the human bodies cells are nonhuman mostly bacteria.

    These bacteria share genetic materials with our cells. It is easy to see that the bacteria are using our bodies to reproduce and survive and mostly to our deteriment.

    Our immune systems are trying to get rid of the pathogens but can't and a chronic cycle of cytokines and inflammation damage our organs. Our bodies harbor many different kinds of bacerial species each causing damage not to mention the co-infections of viruses and fungus.

    We are just walking bacteria factories.


  6. hermitlady

    hermitlady Member

    My dr has a 4 yr old autistic son. Due to all the research he's done for his son's condition, he has found the testing and treatment for me. It all makes sense when you read about all the biochem reactions etc that can be disrupted from missing aminos etc.

    For me, it has disrupted cellular energy production. I just hope I start feeling better cuz my autistic/bipolar daughter is in a manic phase right now and I have to be able to defend myself! :)
  7. Rafiki

    Rafiki New Member

    I'm sorry that my comparison distressed you. I make those kinds of comparisons all the time because I feel better about my own situation when I have some perspective. I don't expect anyone else to find it helpful. We all find different ways to cope with whatever our burden is.

    peace to you,
  8. sorekitty

    sorekitty New Member

    I am mom to 6 yo beautiful boy that has an ASD. I also have been dx with fibro, cfs and now lyme. I honestly don't really know what my dx is I just plan on treating my issues with my dr. My struggles with it ALL are insane. I am on the verge of freaking out on about a daily basis!

    Luckily when I got my Bachelors in Child Development they were teaching that old lame theory was just that! Is that Bettleheim guy still alive? I'd like to tell him a thing or two!

    [This Message was Edited on 01/12/2009]
  9. sorekitty

    sorekitty New Member

    It is way to difficult to really compare because there are so many unknowns.

    So many people think that if you have a high functioning Asperger's kid you have it easy. Not always. They are extremely intellegent and you always have to be on top of their next plot! I honestly love Aspies. There sense of humor, intellegence, ways of looking at the world, etc.

    Sometimes if I am with a mom that has a low functioning kid i feel like "I'm not worthy" but they do not treat me that way.

    As my good friend likes to say . . . autism is autism is autism.

    [This Message was Edited on 01/12/2009]
  10. spacee

    spacee Member

    just wanted to give my opinion. I agree, sometimes, I try to tell myself...well, I could have 'such an so" and that a heavier burden. One of the problems is I look the picture of health and no one takes me seriously.

    But back to the autism. There is a ton of it here in our small town. My heart goes out to the parents. It wasn't here when we moved here 23 years ago that I know of. I know we didn't have a school just for autism like we do now.

    As a grandparent, I want answers too. I worry about having autism in a grandchild. We have severe asthma, ADD, bipolar, autoimmune, CFS the list goes on. Is that the next one?

    Hugs to all.

  11. munch1958

    munch1958 Member

    My LLMD treats many children with autism. He stated during one of my visits last year that the mothers of autistic children are figuring out that it's Lyme plus other bacteria and food allergies to dairy protein and gluten.

    As far as the vaccine issue goes, look at the now defunct LymeRIX vaccine. Many people who had the vaccine had all of the immune suppressive outcomes of Lyme but no spirochetes. Osp A (outer surface protein) is identical to a portion of the AIDS virus producing a Pam-3-cys immune supressive illness.

    MYCOPLASMA has been found in many vaccines. This is the same contaminate that was found in the vaccines the Gulf War 1 vets were forced to take before they were shipped overseas. See the research of Garth Nicolsen.

    The latest research indicates that Borreliosis (Lyme is just one form of the bacteria) is connected to autism in some way. There are many papers emerging on this in Pubmed.

    I saw that movie "Refrigerator Mothers" on TV. It was very heartbreaking and one of the nastiest moves ever made by the medical profession thus far. Historically, if they don't know the cause.... they just blame the victim. That gets them all off the hook.

    It would be much nicer to say something like "We haven't figured that out yet" instead of "You are imagining things".

    Take endometriosis for example. 54% have symptoms before age 23 yet it's known as "the career woman's disease." Like I had a career at age 11 when my symptoms first appeared? There is a study underway where they are culturing endometriosis implants to see if they'll find Borrelia in them. I believe the results will be statistically significant.

    Some folks on this board love nothing better than to knock down ideas and discourage folks from trying things that may help them. I wonder why that is?

    There is a high school student who did a map overlaying the cases of MS and Lyme across the USA. Her results indicated that high tick areas produce more cases of MS. I'd put money on a map of autism cases vs ticks would show a similiar result.
  12. sorekitty

    sorekitty New Member

    I got to see Garth Nicholson and his wife speak about a month ago. It was an eye opener. He spoke to our local Lyme support group.

    You mention so many interesting research. I have endometriosis too and yes you usually don't find out until you try to have children (for me at 33).

    The CA lyme association has a map showing every county in CA has been found to have ticks with lyme, except one up in the Northeast of the state. Yet we hear nothing about it.


  13. gapsych

    gapsych New Member

    You are born with Autism. It is just that it is not usually caught until it is around the time children begin to talk.

    This is also the time children get vaccinated. That is why some people think the vacinations cause Autism.

    If a child get immunizeds and get a reactions it is usually a neurological type of reaction. That is not the same as Autism. It is still tragic but it is NOT autism but may be "Autism like symptoms".

    Autism is present at birth either from genetics are something that has gone wrong during fetal development. Most likely genetics.

    Once again correlation does not mean causation.

    A student in high school does not have the scientific background to sort things like this out.

    Show me the research which is done by real scientist and not by LLMD's and ILADS that say Autism is cause by Lyme. There may be some similarities in certain chemical bodily processes. That is not the same as Lyme causes Autism.

    Statements like this do not help credibility of ILADS where science is going backwards.

    Have you read any articles and research by Simon Baron Coehn? He is one of the world's leading experts in Autism. This is the true scientific research being done.

    Yes he is related to Sasha Baron Coehn. They are cousins. Go figure!!


    ETA. It is not that people like myself do not want people to get treatment to help. It is about credible scientific evidence. Not all symptoms you attribute to Lyme are caused by Lyme. This is where the credibility issue comes in.
    [This Message was Edited on 01/14/2009]