<<<< Bleeding Disorder Patients Warned >>>>

Discussion in 'Fibromyalgia Main Forum' started by jaltair, Jan 6, 2006.

  1. jaltair

    jaltair New Member

    Bleeding Disorder Patients Warned

    Jan 6, 7:06 PM (ET)

    WASHINGTON (AP) - A small number of patients with a bleeding disorder have experienced a potentially life-threatening loss of red blood cells, the FDA and the manufacturer and distributor of a medicine that treats the disorder warned Friday.

    Patients with immune thrombocytopenic purpura, or ITP, should immediately alert their doctors if they experience back pain, shaking or chills, fever, discolored urine or decreased urine output, sudden weight gain, fluid retention, swelling or shortness of breath, Baxter Healthcare Corp. and Cangene Corp. said.

    The rare but sometime severe or fatal symptoms have been observed in ITP patients, the companies wrote in a letter to doctors last month. Reports of the most severe reactions occurred in patients treated with WinRho SDF, a medicine made and distributed by the two companies. Most reported adverse reactions within four hours of treatment, the companies said. The Food and Drug Administration released the letter Friday.

    Deerfield, Ill.-based Baxter distributes WinRho SDF, which is used to treat the disorder, marked by an abnormally low number of platelets in the bloodstream needed for blood to clot properly. Cangene, of Winnipeg, Canada, makes the immune therapy from donated human plasma.

    The companies revised the medicine's label to include the new warning. The revised label also warns that use of the liquid formulation of WinRho SDF can lead to falsely high blood glucose levels in certain types of blood glucose testing systems.

    WinRho SDF also is used also used to protect against the development of antibodies in patients with Rh-negative blood who are given Rh-positive blood, and in pregnancy to prevent an Rh-negative mother's immune system from destroying an Rh-positive baby's red blood cells, the companies said.
  2. chickadee

    chickadee New Member

    I have ITP also and wonder if there is a connection to Fibro. It makes sense if there are organisms in the blood that cause fibro, then it could also cause ITP. I think the trick is to figure out how to route them out and get rid of them without killing the patient!

    My platelets were at 7,000 on Wednesday and I had a treatment of Rituxan. We discussed Win Rho but decided to try Rituxan first. Until I know more about Win Rho, I think I'll probably pass on it if something else will help.
    Won't know for several weeks if the Rituxan has/will help.

    Wake me Up - Do you treat ITP?

  3. jaltair

    jaltair New Member

    It was just a warning that I came across, and since I know some on the Board have ITP, I thought it would be of interest.

    The term "immune" relates to the idiopathic thrombocytopenic purpura (ITP), just another way of saying it.

    Adult idiopathic thrombocytopenic purpura (ITP) usually results from development of an antibody directed against a structural platelet antigen (an autoantibody). Thus the word, "immune."

    Warm wishes, Jeannette
  4. Aussie_21

    Aussie_21 New Member

    I'm sorry. But it is very very rare to bleed to death because of a low platelet count. There is alot of talk on this forum about thromboctopnia that is just not true. Check out the platelet forum www.itppeople.com/lowplatelet.htm...

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