My pressure spikes, has for years. It has a mind of its own and doesnt spike necessarily under direct stress, its totally unpredictable. 10 years ago put on a beta blocker for BP. Without warnings of any kind from family doc, I took it and took it becoming more depressed by the week. A colleague who was studying medicine suggested I see a neurologist to rule out other brain issues. I did and he put me thru many tests and finally asked what meds I was taking. I told him beta blocker for pressure. He said, "that's it, dont EVER use BP meds of any kind, you're body can't handle them." Last year my family prescribed BP meds and I told him what I wrote above, no BP meds EVER. He says, they're all new and different now, so its okay. Gives me BENICAR. I dont take it until last month after he reminds me my pressure is spiking too much and the stress I'm living with is too dangerous, take the BP meds,will ya? I started last month and gradually become the suicidal loon before you I didnt make the connection until Sat afternoon and stopped taking them immediately, I dont advise this for ANYONE ELSE, but if you are taking BP meds and suffer from severe depression, please talk to your doc, it may be a rare side effect but they know it does exist. I still want a psych evaluation, but I definately know I reacted once again to these meds. Antidepressants do the same thing to me.