Can a Nurse Explain this Drug to me (or anyone else who knows)

Discussion in 'Fibromyalgia Main Forum' started by LuvMeCritters, Sep 11, 2002.

  1. LuvMeCritters

    LuvMeCritters New Member

    Why when I was taking Norco (hydrocodone) 10/325, was it not touching my pain, but since I've recently switched to Percocet 5/325, half the strength of the Norco, it helps? I don't understand. Any explanations appreciated.

    Thanks :)

    Regina
  2. LuvMeCritters

    LuvMeCritters New Member

    Why when I was taking Norco (hydrocodone) 10/325, was it not touching my pain, but since I've recently switched to Percocet 5/325, half the strength of the Norco, it helps? I don't understand. Any explanations appreciated.

    Thanks :)

    Regina
  3. TeresaBnGA

    TeresaBnGA New Member

    Norco contains acetaminphen and codeine. Percocet contains an opiod like morphine, oxycontin, methadone. Not sure which one, but Percocet is one of the strongest pain meds you can get and you do get much more relief with less mg's.
    Hope this helps!

    Soft hugs!
    Teresa :)
  4. Shirl

    Shirl New Member

    Here is some information on Percocet. It maybe helpful, also others will share their personal experience with this drug for you too.



    Shalom, Shirl




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    FDA Approves New Percocet Strengths With Lower Acetaminophen Doses
    FibromyalgiaSupport.com

    01-28-2002


    CHADDS FORD, PA -- November 26, 2001 -- Endo Pharmaceuticals Holdings Inc., announced the Food and Drug Administration's approval of the abbreviated new drug application to market Percocet® 7.5/325 and 10/325 oxycodone/acetaminophen tablets that was filed by Endo Pharmaceuticals Inc., a wholly owned subsidiary of Endo Pharmaceuticals Holdings.

    Percocet, the leading brand of oxycodone/acetaminophen on the market, is indicated for the treatment of moderate to moderately severe pain. The new reformulated Percocet 7.5/325 and 10/325 strengths offer proven pain relief with reduced acetaminophen content as compared with previously available formulations of the pain-relieving drug.

    Carol A. Ammon, president and CEO of Endo Pharmaceuticals stated, "The new reformulated Percocet 7.5/325 and 10/325 underscore the strengths of Endo in the marketplace. We believe that we have a robust pipeline that feeds into our growing marketing and sales organization, and the gold standard in pain management with our Percocet products.

    "These new formulations were developed in response to physician demand. These formulations combine the higher strengths of 7.5 and 10 milligrams of oxycodone that physicians have increasingly adopted, with up to 50% less acetaminophen per day than previous formulations. This reinforces Endo's commitment to providing a broad range of safe and effective pain management products," Ms. Ammon said.

    "With this new formulation, physicians can still take advantage of the synergistic action of the two analgesics combined, but without worrying about exceeding the daily limit of acetaminophen," said Nathaniel Katz, MD, Assistant Professor of Anesthesia at Harvard Medical School. "This will really be helpful to patients who may need higher doses of oxycodone to relieve their pain."

    The new reformulated strengths, which are expected to be available in pharmacies within the next week to ten days, will potentially enable patients to take their Percocet on a simpler dosing schedule, allowing them to take fewer tablets per day, and less frequently than the original 5mg tablet. And due to the lower acetaminophen levels, these new strengths may allow physicians to prescribe Percocet 7.5/325 and 10/325 for more long-term use than previously acceptable.

    "The new strengths continue to deliver the dual benefits of oxycodone and acetaminophen, while lowering the risk of excessive acetaminophen exposure," said Lori Reisner, Pharm.D. and Associate Clinical Professor of Pharmacy at the University of California in San Francisco. "The ever-increasing number of acetaminophen-containing products and other over-the-counter pain relievers requires pharmacists to be diligent in reminding physicians and patients about the appropriate level of usage."

    The most frequently reported side effects of Percocet include lightheadedness, dizziness, sedation, nausea and vomiting. Oxycodone can produce drug dependence and has the potential for being abused. Physicians are reminded that the total daily dose of acetaminophen must be carefully considered in the use of any combination product.

    SOURCE: Endo Pharmaceuticals Holdings Inc.






  5. LuvMeCritters

    LuvMeCritters New Member

    I guess Percocet is just made of stronger stuff than hydrocodone then. What a BIG difference it has made. I had NO pain in my neck/shoulder area today for the first time in months! It was WONDERFUL. I actually went out and weeded a little, then once I was a bit tired, but felt like staying out and enjoying the fresh, cooler air we've been having, I layed down in the grass, just relaxing. It was so cool. I hadn't done that since I was a kid...just watching clouds and chillin'. I thought if anybody sees me they're really gonna think I'm nuts. Luckily, we live in the country and you can't see our yard from the road. I just can't believe how great this med works! I felt like a new person today.

    Regina :)