I've had Chronic Fatigue and have been treated for infections since 2005. I found an Infectious Disease Specialist and Professor who reviewed my Lab reports with me. I was being treated for Lyme disease, HHV-6, CMV, EBV et al. It is real important to understand the difference between IgM and IgG infection results: IgM is an active infection IgG is a dormant, past infection A defeated infection goes to sleep (dormant), your body keeps a copy of it to remember how fight it the next time its encountered. All of my lab results were elevated IgG - ie history. No active infections. I had this Specialist and 2 "Externs" quiz me and concluded Sleep Apnea as a more likely candidate for my chronic fatigue. According to the Mayo Clinic, symptoms of Sleep Apnea are: Excessive daytime sleepiness (hypersomnia) Loud snoring, which is usually more prominent in obstructive sleep apnea Observed episodes of breathing cessation during sleep Abrupt awakenings accompanied by shortness of breath, which more likely indicates central sleep apnea Awakening with a dry mouth or sore throat Morning headache Difficulty staying asleep (insomnia) The article went on to say that you may or may not realize the Stopped Breathing part. Your adrenaline may spike to wake you up to catch your breath. Adrenaline (cortisol) will certainly give you insomnia for the rest of the night. Sleep Apnea can occur in children too. I'm in the process of getting a Sleep Study scheduled via my PCP, as I do have all the symptoms.