CFS autoimmune?

Discussion in 'Fibromyalgia Main Forum' started by genevieve, Jun 22, 2003.

  1. genevieve

    genevieve New Member

    Can anyone please point me to any evidence/info on CFS being an autoimmune disease?
    Best wishes to all,
  2. Shirl

    Shirl New Member

    Heres an article from the 'Home' page here on the board that might interest you.

    There is a whole wealth of information on this board for you. Just click on the 'Home' and 'Library' links at the top of this board. If you don't see what you want, then just type it in the 'search' box on those links, its there.

    You can read till your hearts content!

    Shalom, Shirl


    Endometriosis Linked to Autoimmune and Other Chronic Diseases Including Chronic Fatigue Syndrome & Fibromyalgia


    By Laurie Barclay, M.D.
    A cross-sectional survey reported in the Sept. 27 (2002) issue of Human Reproduction showed that women with endometriosis have higher rates of autoimmune and other chronic diseases than do women in the general U.S. population.

    "Women with endometriosis frequently suffer from autoimmune inflammatory diseases, hypothyroidism, fibromyalgia (FM), chronic fatigue syndrome (CFS), allergies and asthma," lead author Ninet Sinaii, from the National Institute of Child Health and Human Development in Bethesda, Maryland, says in a news release. "These findings also suggest a strong association between endometriosis and autoimmune disorders and indicate the need to consider the co-existence of other conditions in women with endometriosis."

    In this population-based survey of 3,680 members of the Endometriosis Association, all had surgically diagnosed endometriosis, 90% were of reproductive age, 66% had a positive family history for diagnosed or suspected endometriosis, and 20% had more than one other chronic disease. Nearly one-third of those with coexisting diseases also had been diagnosed with either FM or CFS, and some of these women also had other autoimmune or endocrine disease.

    Compared with expected rates in the general population of U.S. women, women in this survey had increased rates of chronic disease. CFS was more than a hundred times more common (4.60% vs. 0.03%, P<.0001), hypothyroidism seven times more common (9.6% vs. 1.5%, P<.0001), and FM was nearly twice as common (5.9% vs. 3.4%, P<.0001).

    Women with endometriosis also had higher than expected rates of autoimmune inflammatory diseases including systemic lupus erythematosus, Sjögren's syndrome, and rheumatoid arthritis, as well as multiple sclerosis. Allergies occurred in 61% (vs. 18%; P<.001) and asthma in 12% (vs. 5%; P<.001) of survey subjects overall. Of those subjects who also had FM or CFS, 88% had allergies (P<.001) and 25% had asthma (P<.001).

    "As well as finding an increased prevalence of this wide range of diseases and conditions among women with endometriosis, we found that they reported significant pain and disability and, very worryingly, that there was typically a 10-year delay between the onset of pelvic pain and diagnosis," Sinaii says.

    Potential study limitations included the subjects being relatively young, predominantly white, well-educated, and members of a support group. However, sensitivity analysis confirmed that even if chronic disease prevalence rates were underestimated in the general population and overestimated in the survey, the rates reported in women with endometriosis were still significantly higher.

    "Since women appear to develop symptoms shortly after the onset of their periods and are not diagnosed for years, we don't know whether endometriosis actually occurs at menarche as others have reported or whether it develops over time," senior author Pamela Stratton says. "It's also unclear whether early treatment could prevent chronic pelvic pain from taking hold. It is vital therefore that attempts should be made to diagnose and treat endometriosis in adolescents."

    Hum Reprod. 2002;17(10):2715-2724
    Reviewed by Gary D. Vogin, M.D.
    Source: WebMD

  3. genevieve

    genevieve New Member

    Thanks to you both for your replies, will look up the library but so far I am not convinced it is autoimmune.

    All best wishes to you both,

  4. lucky

    lucky New Member

    After all my research and my doctor's opinion, I also tend to believe that our brain dysfunction results in a suppressed immune system. Dr. Jay Goldstein did a lot of research on it - and his results are proof of this theory.
    It is amazing how many people still are under the impression that for example their amalgan fillings are the cause of their illnesses, etc. Well, what happens is that our immune systems are so dysfunct that they are not coping with any additional stressors, might it be the environment, toxidity, etc.
    It was good to read that there are other people on the board to share this opinion.
    Sincerely, Lucky