CFS & joint hypermobility

Discussion in 'Fibromyalgia Main Forum' started by ephemera, Jan 8, 2006.

  1. ephemera

    ephemera New Member

    Generalized joint hypermobility is more common in chronic fatigue syndrome
    than in healthy control subjects.

    Journal: J Manipulative Physiol Ther. 2006 Jan;29(1):32-9.

    Authors: Nijs J, Aerts A, De Meirleir K.

    Affiliation: Department of Human Physiology-Faculty of Physical Education
    and Physiotherapy Vrije Universiteit Brussel (VUB), Belgium. jo.Nijs@vub.ac.be

    NLM Citation: PMID: 16396727

    OBJECTIVES: This study aimed at (1) comparing the prevalence of generalized
    hypermobility in patients with chronic fatigue syndrome (CFS) and healthy
    volunteers, (2) examining the clinical importance of generalized
    hypermobility in patients with CFS, and (3) examining whether knee
    proprioception is associated with hypermobility in patients with CFS.

    METHODS: Sixty-eight patients with CFS filled out two self-reported
    measures (for the assessment of symptom severity and disability), were
    questioned about muscle and joint pain, and were screened for generalized
    hypermobility. Afterward, the patients performed a knee repositioning test
    (assessment of knee proprioception), and it was examined whether or not
    they fulfilled the criteria for benign joint hypermobility syndrome (BJHS).
    Sixty-nine age- and sex-matched healthy volunteers were screened for
    generalized joint hypermobility and performed the same knee repositioning
    test.

    RESULTS: Compared with the healthy volunteers (4.3%, 3/68), significantly
    more patients with CFS (20.6%, 14/69) fulfilled the criteria for
    generalized joint hypermobility (Fisher exact test, P < .004). No
    associations were found between generalized joint hypermobility and the
    self-reported measures (including pain severity) or knee proprioception
    (Spearman correlation analysis). Knee proprioception was similar in both
    groups (Mann-Whitney U = 1961, z = -1.745, P = .81). Forty patients with
    CFS (58.8%) fulfilled the criteria for BJHS.

    CONCLUSIONS: These data indicate that a subgroup of patients with CFS
    present with generalized joint hypermobility and most patients with of CFS
    fulfill the diagnostic criteria for BJHS. There appears to be no
    association between musculoskeletal pain and joint hypermobility in
    patients with CFS.