CFS SECRET CLOSE TO BEING CRACKED

Discussion in 'Fibromyalgia Main Forum' started by ulala, Jun 29, 2006.

  1. ulala

    ulala New Member

    “Previously Undetected” Virus Implicated In Developmentof Chronic Fatigue Syndrome and other Conditions
    by Editor
    ImmuneSupport.com

    This was posted on this site


    06-27-2006


    Note: This article includes our follow-up suggestions regarding its implications for Chronic Fatigue Syndrome patients.


    Medical science may be just a few research steps away from cracking the secret of Chronic Fatigue Syndrome (CFS), according to news from the National CFIDS Foundation (NCF). Bottom line, states NCF’s Medical Committee: “Parainfluenza Virus-5 plays what the Foundation sees as a predominant and primary role in the development of CFS.”


    This is news that the NCF believes can “change the very nature of this disease.” CFS has been an unexplained ailment, characterized by chronic debilitating fatigue and a combination of flulike symptoms.


    Virus in the Cross-Hairs

    Independent research and detective work funded by the nonprofit NCF has confirmed evidence of a “previously undetected” viral infection in patients with CFS. The research “dovetails” with work by virologists at the private biotechnology research firm Cryptic Afflictions, LLC. It also builds on years of NCF sleuthing for clues in the work of dozens of scientists around the globe, both published and held proprietary.


    The NCF defines the CFS culprit as a strain of the recently named Parainfluenza Virus-5 (PIV-5); formerly called Simian Virus-5, or SV5, owing to its initial isolation in monkey tissue. It is an RNA virus, or “rubulavirus” in the category of viruses known to be associated with diseases such as mumps, encephalitis, and meningitis. And, as an RNA virus, it might be a mutating “chameleon.” At least a dozen strains of mumps virus have been identified, for example.


    It is further defined as a "zoonotic" virus - one that in mutating can be transmitted between animals and people. And, at least as found in an initial CFS patient test performed by NCF-funded researchers, it exactly matches the “SER” strain of PIV-5 virus isolated in diseased swine by German researchers in 1994.


    The Research-Detective Story So Far

    NCF-funded scientists identified a new viral “footprint” in the blood of Chronic Fatigue Syndrome patients, in the form of a deficiency of the Stat-1 protein, which “plays a vital role in immunity.” The researchers then created a “short list” of viruses known to “directly attack and degrade the Stat-1 protein” as part of a viral strategy for evading the host’s immune response. PIV-5 was on that list.


    Meanwhile, they learned that Steven Robbins, MD, a virologist and CEO of Cryptic Afflictions, LLC, had tested blood samples from 56 CFS patients, and cerebrospinal fluid samples from 11 CFS patients, for antibodies specific to an RNA virus he calls “Cryptovirus.” Dr. Robbins found that the vast majority (96 percent) of his CFS blood samples and 91 percent of the CFS spinal fluid samples tested positively for “Cryptovirus-specific” antibodies.


    The NCF also learned that a recent medical journal article suggests Cryptovirus “is most similar to PIV-5” – and that Cryptic Afflictions has “extensive U.S. and international patents pending and owns the intellectual property rights” for Cryptovirus, according to a report from its parent company, Century Pacific Financial Corp.


    Dr. Robbins also found that the Cryptovirus could “cause virtually identical disease in experimentally-infected animals,” according to Century Pacific. Further, he found that “nucleotide sequence data indicate that the virus is pandemic and represents a single virus ‘species’ more akin to measles virus than hypervariable viruses like HIV.”


    In addition to the Cryptovirus’s association with Chronic Fatigue Syndrome, Cryptic Afflictions reports it is also believed implicated in other neurological disorders, including multiple sclerosis and idiopathic (unexplained) epilepsy. For example, the company reports it found Cryptovirus antibodies “in the cerebrospinal fluid and blood of over 90 percent of patients tested with multiple sclerosis.”


    Next Steps for CFS Research?

    At a minimum, Century Pacific says Cryptic Afflictions is now pursuing tests of brain lesions in multiple sclerosis patients, and next plans to ask the FDA for approval of the diagnostic tests. Their testing plans for CFS seem to be unstated.


    The National CFIDS Foundation, meanwhile, reports it is working to get this information out to “medical and health groups that may be interested in further research,” and says it is “interested in funding those researchers who have expertise in the area.”

    The NCF is an all-volunteer patient organization with no paid employees, and is funded solely by individual donations for the primary purpose of funding CFS research.


    To review the NCF press release on this discovery, as well as a highly detailed, sourced report on the National CFIDS Foundation Medical Committee’s detective work, titled “Parainfluenza Virus-5: A new paradigm and a serious host challenge,” visit the Foundation’s site at http://www.ncf-net.org/Discoveries.htm

    What does this mean for you?

    1. Clearly, this and further research that may establish Chronic Fatigue Syndrome as a pathogen-triggered disease would lend medical validity to the condition.


    2. Further, increasing knowledge regarding this virus or viruses may lead to preventive measures such as vaccines and epidemic surveillance, and/or effective treatments.


    3. This news of the dedicated efforts by NCF-funded researchers and others underscores the importance of contributions to CFS research. We at Pro Health are proud to report that as a patient-owned company we have raised and donated more than $2.5 million to CFS and Fibromyalgia research to date, and contribute a portion of all our product sales to this cause.


    [This Message was Edited on 06/29/2006]
  2. alaska3355

    alaska3355 New Member

    Hopefully this will speed up an effective treatment for CFS.
  3. Marta608

    Marta608 Member

    However, I don't think there's one cause to be found for this illness at this point, where so many of us have had it for so long. That's not bad news, it's just to say that we shouldn't sit back and wait for a magic pill.

    Diet, diet, diet! (nag, nag, nag lol)

    Marta
  4. leannebug

    leannebug New Member

    Is it also linked with FM? I have that, but in the past year and half was diagnosed with idiopathic cardiomyopathy. They are "guessing" that one came from a strep-type illness that went untreated.

    It's my sneaking suspicion that they are all somehow related, as they are all "muscular" and also of "unknown origin".. blah blah blah.
  5. Scapper

    Scapper New Member

    Thank you so much for your research and sharing it with all of us!

    I'm hopeful that at least research is being done out there. However, I don't think there is a one main virus at the root of CFIDS.

    Well, at least not in my case. All I know is my own body and how CFIDS has played out with me. I have tested positive for many viruses, many heavy toxins and everything seemed to hit in one big cluster all at once. Onset can be different for us all and the culprit may not be exactly the same either, regardless of one's symptoms.

    I will definitely have my practitioner check this out for me, since the layers of this illness seem to be many fold for me.

    Thanks again :)

    scapper