"there are many causes." No causes are known - at all. so any Dr. saying that there are many causes are simply making it up. "Cortisone in low doses reduces inflammation" Yes but by local injection. It is not a systemic anti-inflammatory. This is one of the reasons why it is contra-indicated for SLE - and ME/CFS. "increases energy" What evidence is there for this? What studies can you quote? "low doses actually raise immunity" What does this mean? Do you mean makes you less likely to get an infection? How could cortisol possibly make you less likely to get an infection? Even at low doses? I am trying to understand your rationale for using Isocort in a scientific way.