Well, here it goes: I finally got into the doc's office a week ago - not in full flare, but enough that when she touched me, I pushed her away - and was she shocked! She had no problem giving me something stronger for pain than Ultram - but told me not to take the two together. And, now, I am feeling much better. She also took me off of Wellbutrin and put me back on Effexor XR not only because of the depression, but also because she said that Effexor does have a certain amount of analgesic components which helps with the pain. But, coming off the Wellbutrin was miserable, and getting back on Effexor (first 37.5 x 7 days, then 75mg. every day) was a mess. I became teary, unsure of myself and how others throught of me; thinking I did not fit in and on and on. I was a mess. But, thanks to FMily, I was put on the right track - and I am doing much better mentally. I just want everyone here to know that there are days whenever you cannot handle the situations at hand; and support groups, like the ones I belong to are a lifesaver. If any of you do not have a daily support group, please consider finding one - they are really heaven-sent. Those personal monthly support groups that you attend are fine for info, a get-together monthly, but these that are online are a blessing. And, that is my message. Hope this helps others being changed from one medicine to another. It does get better. Wishing all many hugs and rainbow wraps - from and with Love, LindaD.