Hi out there. Anyone experience unexplained chest tightness that is not asthma? I have CFS and one of my symptoms is this chronic chest tightness. My upper airway -- trachea, it seems, not the smaller bronchi or aveoli -- is always to some degree "tight". It's uncomfortable breathing, but I can indeed breath deeply, e.g., lung volume tests are normal. I am sure that it's not asthma, since I had asthma as a child and this isn't it; since asthma medicines that worked fine when I had asthma don't even alleviate this chest tightness whatsoever; and since a methacholine challenge test triggered a hint of standard asthma, but not exascerbation of my chest tightness. I think this chest tightness may be chronic inflammation, a "local manifestion" of Dr. Pall's NO/ONOO cycle. Which may or may not be a manifestation of RUDS/RADS. This is my latest theory, anyway. Any thoughts on this? Anyone with similar experience?