I have had CFS, IBS, and depression for two years now. I've also been treated for Candida, h.pylori, parasites and thyroid, but my symptoms only partially resolved. A few weeks ago, my doctor came across new research about chronic neurotoxins. These environmental toxins enter your body (via tick bite, spider bite, certain airborn molds, fresh water algae, etc.)and circulate through your system wreaking havoc on the immune system. What they have found is that some people are genetically unable to eliminate these toxins from their body, and this is turning out to be a major factor in many people with CFS, FM, IBS, depression and autoimmune diseases. The testing and treatment are an easy process, and may have a great effect on reducing or completely resolving symptoms. It is worth looking into. You can find more information on immunesupport.com (search chronic neurotoxins) or (Edited to remove URL). You can actually take preliminary tests at chronicneurotoxins.com--a visual test and symptom/exposure survey--to know if you are a candidate without even having to see a doctor.