Chronic Pain Gene (neuropathy) discovered...

Discussion in 'Fibromyalgia Main Forum' started by victoria, Sep 10, 2011.

  1. victoria

    victoria New Member

    it will be interesting to see what comes out of this...

  2. Mikie

    Mikie Moderator

    I saw this too. With new genetic research, each day seems to bring discoveries of defective genes which are responsible for, or related to, medical conditions. Often, there are several defective genes found in these conditions. Some with the conditions have all defective genes and some may have only one or two. This could help explain the differences in people with illnesses. It could also help explain why some of us are sicker than others and/or respond differently to treatments. It could also help explain why many of us have more than one condition.

    Longitudianal studies of identical twins has revealed that their genes are identical at birth. Decades later, there are big differences in their genetic makeup. Researchers believe that their environments explain the differences. With all the pollution and toxins to which we are exposed, it is possible these stressors make us genetically predisposed to illness. It would also explain the increase in people with certain illnesses. Once we are changed genetically, we can pass our defective genes to our children. This could explain why some illnesses seem to run in families.

    I'm no researcher and my inferences may not be correct but I can't help but wonder.

    Love, Mikie

  3. ellikers

    ellikers New Member

    It sounds so daunting to think it's in our genes ... I think when people hear "genes" they think permanent.

    On the brighter side, it gives me major hope that researchers and treatment specialists are recognizing that we can change our brains overtime to unwind these pain signals run amuck. Our brains wound themselves into these places in the first place, and there are things we can do to change them. I've had a lot of luck recently using this model of "neuroplasticity" (plastic meaning changeable) ... I wish we could use the best of the best treatments for everyone super early in their progression ... I have a feeling we could stall a lot of these destructive diseases to the point that we just have sensitive bodies that need some extra attention and care (but not be debilitated).

    A girl can dream .... ;)
  4. Mikie

    Mikie Moderator

    Wire together. The earlier we can stop the hard wiring of harmful brain activity, the better. It's never too late, though, if we can figure out how to unwire our brains and rewire them to function better. One example is visual training for third nerve injuries following head trauma. Both my daughter and I had bad concussions at about the same age. We ended up with third nerve injuries and were seeing double. Most docs told my Mom at the time that there was nothing which could be done. Then, we found a wondeful eye doc who did visual training. For months, I sat at machines, staring at the screen doing exercises like lining up a straight line through a circle. Slowly, my brain started to respond and the double vision was gone. This doc was still practicing when my daughter had her accident. She also was successful with visual training. A lot of docs still don't believe in it.

    When I could still wear contacts (before Sjogren's) I took to monovision so fast that they couldn't believe it. Same with my progressive glasses. We think the vision part of my brain is more plastic because of all the visual training years ago.

    I've tried something with FMS pain, not the tender point pain but general pain in an area of my body. For instance, when I go to bed and my hips and legs start to hurt, I say out loud, "Stop it, you're not real." In other words, the pain isn't due to any injury; it's just rogue pain signals from my brain. It has worked. It's like I've reached out and smaked my brain and told it to knock it off. It doesn't work every single time but it has worked often enough that I've felt I was onto something.

    Love, Mikie
  5. ellikers

    ellikers New Member

    The neuronal nerding out continues ;) I swear you and I are on the same wavelength about a lot of this stuff Mikie ...

    I use a similar technique with pain, I just repeat "this is in my brain, not my body" ie I'm not injured, my body doesn't need to tense, and mount a defense, etc. Then I visualize quieting down the activated areas in my brain that are lighting up with the pain signals.