Coleus Forskohlii herb for thyroid - week 6 update

Discussion in 'Fibromyalgia Main Forum' started by spiritsky, Apr 12, 2007.

  1. spiritsky

    spiritsky Member

    Still taking this amazing herb for thyroid support. It has many other benefits as well. I'm still off my thyroid medication and have had to drop the daily dosage of the herb, it seems to build up in the body over time and I started feeling a little spacey something like having too much thyroid hormone...I'm just taking 25mg (standardized at 18% forskolin) every other day now, and cycling it with 30mg Ginkgo/200mg Gotu Kola (standardized at 24% Ginkgo Flavone Glycosides, 6% Terpene Lactones). It's really working, I have much more of energy/vitality during the far anyway...will keep posting with updates.

    Other herbs I'm taking are mostly for adrenal support - Ginger, Ginseng, Milk thistle, Licorice, Asragalus, etc...

    Here's a write up on the herb for those interested.

    Coleus Forskohlii Herb Extract
    This "power" herb has an active ingredient in it called forskolin. It has been used in ayruvedic medicine for many years. Forskolin's basic mechanism of action is that it increases the amount of cyclic AMP (adenosine monophosphate) in cells by activating an enzyme called adenylate cyclase. Cyclic AMP (cAMP) is one of the most important secondary messengers in the cell. It is considered to be one of the most important cell regulating compounds.

    Under normal circumstances, cAMP forms by adenylate cyclase activation due to hormonal stimulation at the cell receptor site. However, forskolin seems to bypass this reaction and allows for an increase in intracellular cAMP to occur. Why is it important to increase cAMP levels? Well, there are several benefits of this to athletes including relaxation of the arteries and smooth muscles, lowering blood pressure, enhanced insulin secretion (which can help drive carbohydrates and protein into muscle cells for energy and recovery), increased thyroid hormone function (which can help enhance metabolic rate), and significantly increase lipolysis (fat burning). Forskolin also seems to benefit other cellular enzymes as well.

    The breakdown of fat for fuel (lipolysis) is actually regulated by cAMP. Forskolin has been shown to not only enhance lipolysis but it may also inhibit fat storage from occurring. This is very good news for individuals trying to lose bodyfat and get lean. Another way that forskolin may allow for fat loss to occur is by stimulating thyroid hormone production and release. Thyroid hormone controls metabolism and can enhance metabolic rate, which may translate into more fat loss.

    One of the overlooked benefits of forskolin includes its stimulation of digestive enzymes, which can allow individuals to digest and assimilate their food better. It has been shown to increase nutrient absorption in the small intestine.

    Forskolin has been shown to be safe and effective and has a great amount of potential as a sports supplement. As with most dietary supplements, more human research is needed but the future looks bright for this compound.

    Forskolin is a labdane diterpene that is produced by the plant Plectranthus barbatus. Forskolin is commonly used to raise levels of cyclic AMP (cAMP) in the study and research of cell physiology. Forskolin resensitizes cell receptors by activating the enzyme adenylyl cyclase and increasing the intracellular levels of cyclic Adenosine Monophosphate (cyclic AMP or cAMP). Cyclic AMP is an important signal carrier that is necessary for the proper biological response of cells to hormones and other extracellular signals. It is required for cell communication in the hypothalamus/pituitary gland axis and for the feedback control of hormones.


    -Inhibition of platelet activation and degranulation.
    - Inhibition of mast cell degranulation and release of histamine and other allergic compounds.
    - Increased force of contraction of the heart muscle.
    - Relaxation of the arteries and other smooth muscles, vasodilation.
    - Increased insulin secretion.
    - Increased thyroid function (and therefore metabolic rate).
    - Reduced adipose assimilation and increased lipolysis of fats.

    [This Message was Edited on 04/13/2007]
  2. elliespad

    elliespad Member

    would be a good thing. Sounds like a good herb to put on my "Have to read up on this someday" list. Thanks, and hope you have continued success with it.
  3. desertlass

    desertlass New Member

    maybe if you added "thryoid support" in your post, more people would jump in. Just an idea. I had never heard of this herb, nor what it was for.

    Good luck!
  4. spiritsky

    spiritsky Member

    It's interesting that you mentioned the heparin. I was just thinking the same thing a few days ago...I have a neighbor who had to take heparin as part of the FFC protocol (she has FMS). I was thinking that the coleus, since it's a vasodilator, might help people who have issues related to thick blood since it would help bring oxygen to the cells more easily and hence more energy...

    By the way, I'm still using it and I still think it's great stuff...
  5. spiritsky

    spiritsky Member

    My thyroid dose was 37.5 mcg time released T3. It was not a huge dose, but without it I was very dysfunctional.

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