Have you seen this article? I'm so excited, because it means research continues, and progress continues in the health area. This was found by researchers in a Chinese University, showing "the breakdown of cellular recycling systems in the neurons of the spinal cord and brain of ALS patients that result in the nervous system slowly losing it's ability to carry brain signals to the body's muscular system. Without those signals, patients are gradually deprived of the ability to move, talk, swallow and breathe." Proteins perform significant functions in cells and two of the researchers found a key protein, ubiquilin2 as the key protien in the ALS mystery. It's suppose to repair or dispose of damaged proteins; however, there is a breakdown in ALS patients and it does not do this, so the damaged proteins pile up and block the signals in the spinal cord. They feel this might also be connected to other diseases, such as Alzheimers, dementias, Parkinson's, and one article I read even mentioned Lupus. Could it perhaps have something to do with CFS and fibro??? Right now my sister has a tentative diagnosis of ALS vs. nerve compression in her neck, and is waiting on neck surgery. After that the final dx will be made. I pray daily for her. Wouldn't it be something to have future families not have to face a death sentence? And maybe see an end in sight for our problems also?? Does anyone else feel there could be a connection for our DDs?