I would like to know what mycoplasma are and how they could be involved in in ME/CFS or fibromyalgia or other ‘invisible illnesses’? Reply: Mycoplasma species are very small, slow growing bacteria that do not have a cell wall like most bacteria. This allows them to enter cells where they can hide and interfere with cellular metabolism, steal nutrients and cause havoc with organelles like mitochondria, cell membranes and even the nuclei of cells. When these cellular structures are damaged, the organs and tissues that are host to the Mycoplasmas become damaged. Eventually this can result in certain signs and symptoms, depending on a number of factors, among them the tissues invaded, other toxic exposures, and the immune and genetic susceptibility of the host to certain diseases and illnesses.