Hi, I posted yesterday and thank-you for the replies. I'm debating about taking cymbalta but forgot to ask all of you if you can continue to take pain meds if needed. Right now I take either Ultram or Vicodin. I try to limit them as much as possible especially vicodin because of liver damage. I'm concerned about still being able to take the meds as I get my dosage of cymbalta from 30mg/day up to 60/day. I asked the Dr. and he said try to cut back on pain meds but as you know thats difficult since almost everyday the pain is severe.(easy to say cut back when you aren't experiencing the pain) Fibro-a terrible DISEASE. Thanks for all your help and listening.