I just started on 30mg of cymbalta for 7 days and have just moved up to 60mg on day 8. I have been in such pain with knots all over my back and terrible constant spasms for years, and tried everything you can possibley think of. I am stunned that the the cymbalta is working very fast. I woke up on my back last night and was not in pain. I have not slept on my back in years. I have no side effects from it thus far.I also took part in a commercial for the first FM specific drug called Lyrica.