Cymbalta RLS

Discussion in 'Fibromyalgia Main Forum' started by revlcb, Mar 11, 2007.

  1. revlcb

    revlcb New Member

    Dr. put me on Cymbalta for pain releif and fatigue. First day on Cymbalta wasn't so great...constant headache, fatigue, diarrhea and nausea. These are all known side effects. During the night I had great difficulty falling and staying asleep due to restless legs. I've never experienced RLS before the Cymbalta and searches on the internet haven't showm me much.

    Has anyone here experienced this?
  2. dononagin

    dononagin New Member

    I've had RLS for years but it does seem like it got worse with Cymbalta..
  3. sueliza

    sueliza New Member

    I have heard that all of the new ad's can make RLS worse. I am sorry I don't remember the reason. I was on Zoloft (still trying to get off!) for a few months and it made my RLS horrible.

    Try a search of SSRI's or SSNRI's and RLS and see if you see anything.

    I tried Cymbalta too and only took one dose and was nauseous for a week. My pharmacist said she had seen a lot of people who could not tolerate it. I hope your symptoms let up soon! :)
  4. revlcb

    revlcb New Member

    Anyone who's on Cymbalta have issues with feelings of low blood sugar (I'm hypoglycemic)?

    Will have to do some more research on this med. What I've found so far is pretty scary

    [This Message was Edited on 03/13/2007]
  5. lafont

    lafont New Member

    hi revleb. please tell me what you know about cymbalta. I started today, and have felt nausea,and occassional pain on one side of head and diarrhea. WHAT ELSE DO YOU KNOW. I don't really want to take them but I trying to get on disability,haven't been able to work for 6 months, and I have not had success with supplements,to get better. I need to get better to get back working or get on disability. I don't think any judge is going to give me disability unless I am on their drugs. I would rather search out other avenues, but then I am not working with the dumb system
  6. revlcb

    revlcb New Member

    I do searches on my medications...not only from the drug sites (which only tell you how wonderful the drug is and a few side effects) but also "Cymbalta message boards". I find the message boards tell you the real thing as they're just like ours...real people.

    What I've found is that if you're aflicted with depression then many people have found Cymbalta to be great. Quite a few find the medication to be a godsend for their pain relief. But, there's just as many that can't justify the side effects.

    I know that anti-depressants immensely help many many people and for this I'm grateful. They're just not for me. As mentioned, Cymbalta is the third anti-depressant I've tried. With each one I couldn't get past the side effects. What's worse, the FMS symtoms or adding to those symptoms with more side effects? It's a personal choice.

    So, if you've not tried an anti-depressant in the past I'd say give it a try. You just may be someone that it's a wonder drug for. You can only judge for yourself after experiencing the effects/side effects.
  7. revlcb

    revlcb New Member

    Ok, I spent most of last night tossing and turning with the RLS - no it's more like Restless Body Syndrome. I feel like I'm about to jump out of my skin. This is not good...I look like I have Parkinson's I'm twitching and jumping around so much.


    So much for this wonder-drug. Will keep on seeking.
  8. HRgirl

    HRgirl New Member

    As with most Anti-depressants - it takes 4-6 weeks for the side effects to diminish and yes in some - they can't tolerate, but to judge after 3 days isn't giving you or the medication a chance.

    I was put on Cymbalta for my depression (due to CFS and FMS) and pain. I had some pretty bad side effects that started to lessen after 3 weeks. One of those was RLS which my doctor put me on 1mg of Klonopin a night for that and it helped greatly.

    I cannot tell you how much it has helped my pain. It has been a good medication for that. Weird thing is, it doesn't help completely with the depression. My IBS is starting to subside again. I have been on it for 6 months.

    Worse side effect is dry mouth, some weight gain and panic attacks. I don't know if it is a side effect of the symbalta or not.

  9. mujuer

    mujuer New Member

    I have had rls way before I was put on Cymbalta and it just got worse. My rheumy put me on Requip for rls and it is great but it doesn't stop the twitching from above the waist. I just came out of a terrible flare with muscle spasms all over. I was put on the strong muscle relaxer, cyclobenzeprine and it saved my life. I had even gone to the e.r. The f.d.a just approved Cymbalta as the first drug ever to treat fibro. I know it has helped me alot with my pain. I know that I have to decrease my coffee intake as I take it in the morning and it gives me the shakes if I have to much coffee. With any side effects, I would call your dr. before you go off of anything. It isn't much fun going off of Cymbalta because I went off in Sept. thinking it wasn't doing me any good. Boy was I wrong. Anyway that is just me.
  10. suzette1954

    suzette1954 New Member

    I wish I had read this first. I took the 1st one at 9:30 and Im waiting for all of the awful symptoms to start!!

    My PC gave me 6 weeks of samples yest because Ive been having a terrible time with hotflashes and he took me off of Zoloft that Ive been on for many yrs and put me on this. I just had a stomach virus for 10 days and finally started eating alittle on Sunday. Im still not over it and I CANNOT go through this again this soon.

    Its too late to try to throw it up. Im on 30 different meds that would have killed anyone else by now. I will have to be put in the hospital if I get these symptoms this soon after being sooo sick. I cant fight any illness with the fibro and now I will probably make myself sick sitting here waiting for the bad stuff to start.

    How ironic! I was up half of last night with restless leg syndrome and now Im going to have it every night??

    I'll let you know what happens.

  11. HRgirl

    HRgirl New Member

    Above, you will see it takes 4-6 weeks for full effect and side effects to subside.

    I think this is a wonderful drug and yes I had problems with RLS but my pain is about 75% better and there is medication for RLS.

    Throwing up, does not sound like fun.
  12. kjschlotte

    kjschlotte New Member

    I have been on Cymbalta since July 2006, Since that time my pain has decreased dramatically, it took about 2 months to kick in but like i said before that pain is significantly less.

    How ever i do agree that is helped pain more than depression, currently on 60mg but going to 90mg to see if it helps the depression
  13. revlcb

    revlcb New Member

    I guess I need to contact my Dr.

    I can't go to work and expect to be productive for 8 hours with my body spasming and jerking and having hypoglycemic blood sugar crashes.

    I'm also not loving the thought of taking additional meds to get me through side effects. If I had previously had RLS or depression this would be a mute point.

    Thank you all for your encouragement, whatever your opinion. I appreciate hearing all views.

  14. roge

    roge Member

    yup, any seretonin drug can potentially cause rls as rls is likely due to low dopamine and seretonin antagonizes dopamine or blocks it. I guess i shouldnt say "cause" but definitely a strong association here, of course do most dr.s inform us of this, noooo

    even tryptophan can "potentially" cause or aggravate existing rls as it is a seretonin booster, i was on it for 1 year and then myoclonic jerks started (maybe rls but still trying to figure it out) , but also the jerks could be from tequin adr (an abx) or just the start of my CFS (virus in my CNS).

    just interesting how you get jerking as a symptom, are they lightning like fast (myoclonic)? and when do they happen, while you are asleep, falling asleep and what about when awake in daytime?

    i would be cautious here with cymbalta or any other seretonin med, your reaction and so quick could indictae your problem could be dopamine related as some research is linking FM with low dopamine.

    you might do better with a drug that increases dopamine and epinephrine or one that is 50 -50 with seretonin and dopamine as not sure but cymbalata I believe is mainly a seretonin booster and if it does affect dopamine then it does so minimally. each person is different, but dopamine can be as effective if not more for reducing pain and decreasing fatigue than a seretonin drug. In fact it is believed that increasing epiniphrine levels (post cursor of dopamine) is good for lowering pain.

    still trying to figure out if the myoclonic jerking I get (mainly at sleep onset) but also sometmes in daytime when awake is actually RLS or another sleep disorder on the myoclonus spectrum. As I don't get the restless symptoms where I feel like I have to move my legs or the feeling of ants on my legs, just the jerking.

  15. revlcb

    revlcb New Member

    for the information. I will definitly call Dr. tomorrow.

    I didn't take the Cymbalta today and I'm still jittery and entire body.

    The muscle jerks were not myclonus. I've experienced those and these aren't it. I feel as though I'm a doll being controlled by strings overhead. As if something's in my body controlling it. I've GOT to move. If you've seen a a Parkinson's sufferer...that's me. Not jerky, just gotta move.
  16. revlcb

    revlcb New Member

    I've had enough. Day 5 and I'm more jerky than ever. No more Cymbalta for me.

    I called the Dr.'s office and talked to the P.A. and informed her of my decision. The Cymbalta was originally prescribed for fatigue and pain, so hopefully when I go to see the Dr. this coming week he'll prescribe Provigil as I've used it in the past with good luck. Now, pain meds are a different matter. The strongest pain med he's ever prescribed has been Motrin 800, with little effect against the pain.

    This is one Dr. that absolutely hates to refer out to a specialist as I'm on an HMO. So, hopefully things will improve.

    Will keep post up to date.
    [This Message was Edited on 03/17/2007]

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