Haven't been on here for a while -- busy with family, etc. But I had a check-up w/my CFS doc after blood work and am happy to find that my thyroid and cortisol numbers are really good. So good, that my dosage is being decreased for both. What I didn't tell her is that I was not taking the cortisol (5 mg/day) on a regular basis anyway. I could tell it was 'coming back online' so was only taking it on high-stress days or during an illness. The thyroid being decreased is T3, but the Synthroid is going up by 25 mcg. -- trying to find the right balance. I'd heard a long time ago that with the right treatment, the adrenals can begin to produce cortisol again. Over 10+ years I watched my cortisol number skyrocket then gradually flatline. I'm very happy that the flatlining is apparently over.