I don't post on here very often. But, suddenly I feel a need to talk to someone. I feel so depressed! It's like an emptiness, an isolation from everyone, no motivation to do anything! I originally was dxd with anxiety along with Fibro, and started taking Effexor XR about 4 1/2 years ago. I was doing well and I really wanted to get off of the Effexor, last spring (a year ago) but my Neurologist said I'd need to go see a psychiatrist for help getting off of it. So, I went to see a new psychiatrist since my old one had moved away. After seeing her a couple or 3 times she did wean me off of Buspirone, but told me that she didn't think it was a good idea to take me off of Effexor. She felt like I was just barely in control, and any kind of change in my life seemed to really be hard on me and caused me to be anxious! And she also felt like I would be in more pain! So, she ended up increasing my dosage instead over the past 9 months! But, after feeling like I was doing so well, all of a sudden I feel so depressed! Could increasing my Effexor make me feel MORE Depressed instead of better? I don't understand it? My Rheumatologist has told me before that he also felt like I was just barely hanging on to any kind of control of my Fibro too! So, he hasn't wanted to take me off of anything or change any of my meds. Any little thing, overdoing it, or getting really tired and exhausted and I go into a flare that can last weeks! Just one more detail you should know. I have had a hard time turning loose of my youngest daughter. She graduated from college April of 2004 and 2 months later she moved to Germany to work in the mission field there in East Germany. Her fiance went with her. Then they came home last July, for a month to get ready for their wedding, and got married last August. Then returned to Germany. When they first went to Germany they had committed to stay there working with the church there for 2 years, but this past January they decided to commit another 2 years! So, they won't be coming home until the summer of 2008! We have always been very close and I was so involved in her life, turning her loose has been painful! We do have one son and his wife and baby that live here close, and I enjoy being able to see them often! We also have our oldest daughter and husband and baby that live about 8 hours away, so I don't get to see them really often. But having the youngest on the other side of the world is tough! They were here in April for 3 weeks and our oldest daughter and her baby came and stayed for 2 weeks so they could see them too, and we had such a good visit and so much fun! Then when they left it hurt again! Is it just the situation or is it the Effexor?