I have a question about coffee enemas for you. I have been using cholestyramine (alternating with brown seaweed) to try to remove mold poisons from my body. What I have found is that these don't give me much of a reaction unless I combine them with some fish oil (or flax oil). Then they totally knock me out and I get quite sick. Below is an explanation kindly provided to me by Dr. Mary Beth Short-Ray. She is an osteopath who suffered from mold poisoning herself and then wrote a very good intro book called "Surviving Toxic Black Mold Syndrome." Her explanation seems to be suggesting that my gall bladder is an issue. That seems reasonable to me, since it seems to work in fits and starts. I get a whole lot more gurgling type feelings/sounds when I do use the fish oil, too. I'm wondering if there are other things that could make this process easier. Like, what do you think would happen if I tried coffee enemas? Do you have any other thoughts? Thanks! ** I think I may have come across the answer to one of your questions specifically on why csm plus fish oil causes such an intense reaction in you. In Patricia Kanes PK protocol book entitled The Detox Book it is described that the mold toxins ie neurotoxins logde in the gallbladder. CSM works at the opening of the gall bladder (spincter of Oddi) by binding to the toxins and allowing them to be excreted in the stool. They explained that if the gall bladder is sluggish and does not push out the bile like it should and since fats stimulate the gallbladder to contract iinto action ie pushing out the bile...you may have experienced a more intense reaction because this time the CSM actually did work whereas before it did not because you have a sluggish gall bladder. I am guessing that you still have a gallbladder based on this reaction. I am wondering what would happen if one did not have a gallbladder as I do have more than a few mold patients who ended up having their gallbladder removed because of mold symptoms that imitated gall bladder attacks because of mold toxins lodging in the gall bladder. In fact in Dr. Kanes book, they have recipes for CSM to be mixed with heavy cream to stimulate the gallbladder to contract and release toxins so they can be bound.