Hi, I've had FMS/CF/ME since 2004 officially but probably had it since 1997 when I first started having unexplainable pain that didn't show up on xrays. My specialist who I am very lucky to have (DR Laura Black with the Hunter Hopkins Center in NC an associate of Dr Charles Lapp) has prescribed me Methadone for the past several years and it worked beautifully only last fall it started having nasty side effects of nausea and severe vomiting whenever I ate. Now I am in the midst of searching for something to replace my pain management. Dr Black currently has me on Gabapentin 600mg and Soma 350mg 2x daily along with a Butrans pain patch 10mg. The patch is not cutting it at all! I am having alot of breakthrough pain, Thank God I still have some Methadone left to take for rescue pain. Most days my pain level is L6-8 by mid afternoon to evening. Yes I am nauseous and sick after I eat my evening meal if I take the Methadone but it's the price I pay for pain relief. I am going to talk to Dr Black next week about other options for pain control. What are your thoughts, experiences with Dilaudid, Morphine and Opana? Due to gastric bypass surgery I don't absorb the same as regular people so cannot take extended release pills and my surgeon prefers I take capsules, liquids or injectable forms of medicines where possible. Do the above medicines come in these forms? I also am hypothyroid and worry about the effects of narcotics combining with my thyroid medicine Amrour. Any thoughts, discussions there would be greatly appreciated as well. Thanks for all your help!