DLPA

Discussion in 'Fibromyalgia Main Forum' started by UnicornK, Apr 19, 2006.

  1. UnicornK

    UnicornK New Member

    I just got back from my doctor and he reccommended DLPA. I looked it up and got some interesting info: (Kind of long...I copied and pasted.)

    "The pain reliever DLPA (D,L-phenylalanine) contains two forms of the amino acid phenylalanine. The "L" form is a natural substance found in protein-rich foods; it's believed to bolster mood-elevating chemicals in the brain, such as dopamine and norepinephrine. The "D" form of phenylalanine, on the other hand, is made synthetically in a laboratory; it appears to block a nervous system enzyme that amplifies pain signals. In other words, it may prevent the breakdown of the brain's natural narcotics.

    DLPA supplements combine the "L" and "D" forms of phenylalanine, packing a potent one-two punch, and quickly relieving minor depression and physical discomforts.

    Health Benefits

    Research indicates that DLPA can be an effective part of an overall program to fight chronic pain and beat the blues, including the mood swings of premenstrual syndrome (PMS). Some sources contend that DPLA can increase energy and mental alertness, as well as heighten the ability to focus in individuals with attention deficit hyperactivity disorder (ADHD).

    Combined with ultraviolet (UVA) light therapy, various forms of phenylalanine have also been proposed as a treatment for vitiligo, a somewhat mysterious dermatologic condition characterized by the development of white, pigment-free patches of skin. In one study, Parkinson's disease patients experienced some relief from symptoms when taking DLPA and doing a pain relief therapy called TENS (transcutaneous electrical nerve stimulation). However, rigorous research into these uses is still needed.

    Specifically, DLPA may help to:

    # Ease depression. Several clinical studies have been done to examine the effect of DLPA supplements on mood. In one trial, 12 of 20 depressed men and women who took 75 to 200 mg of DLPA a day reported being free of depression after nearly three weeks of treatment, and four reported feeling somewhat better.

    For relief from the blues, DLPA appears to be most effective when combined with other natural antidepressants, such as the herb St. John's wort or the nutritional supplement SAMe (S-adenosylmethionine). One smart approach might be to try one of these other widely tested dietary supplements first, and then add DLPA to the mix if depression persists.

    Interestingly, the combination of DLPA and St. John's wort performs similarly to the newer, long-acting prescription antidepressant, Effexor-XR. Like that drug, the supplement-herb combo raises levels of at least two mood-elevating brain chemicals: norepinephrine (from the DLPA) and serotonin (from St. John's wort). In addition, like Effexor, DLPA suppresses appetite by promoting the release of a hormone that curbs appetite, a useful side effect for those who seek solace for their depression by raiding the refrigerator.

    # Allay chronic pain. Although more research is needed, there is some evidence that DLPA can help to relieve certain types of chronic pain, including muscle aches and persistent arthritis-related pain. The supplement appears to stymie the actions of a pain-inducing protein called enkephalinase. Some scientists speculate that DLPA also helps by boosting the effectiveness of narcotics and other pain medications you might take.

    Some proponents believe that DLPA may be a more effective pain reliever when combined with GABA (gamma aminobutyric acid), a sedating amino acid that blocks pain signals in the brain."
  2. UnicornK

    UnicornK New Member

    I see a pain management specialist who happens to be up on FM/CFS etc... And he (obviously) is open to other methods of healing.
  3. elliespad

    elliespad Member

    I have been ranting about it for ages, noone else seemed to try it. It is my ONLY pain med anymore. It also helps with tremors, and staying alert. I use 1000 mg. in morning, but you can take more if needed. Just don't take later in afternoon as it may keep you awake. Is CHEAP, about $10 in any health food store. L-Tyrosine will also help with staying alert.

    I LOVE amino acids, I also use L-Tryptophan for sleep,(about 4 or 5 years now) also must take B-6 with Tryptophan. Started using GABA about 4 months ago for sleep, and helps even more.