Does anyone take Nician? Neurtiron

Discussion in 'Fibromyalgia Main Forum' started by Bruin63, Sep 4, 2009.

  1. Bruin63

    Bruin63 Member

    my primary doc has rx'd this for me, and from the side effects listed at rx.
    I am hesatate to try it.
    my hubby is concerned, as heart problems do run in my family, on moms side.

    my cholesterol is 250, about 10 about the max. so i am also worried about it.

    also i now have dry kidneys, and blood in my urine, so i am about to have a urogilist (sp?) do a bladder exam.
    not thrilled about that either.

    i am also being put on neurtrion, 100mg 2x a day.
    i had bad experiences 8 years ago, but my ruhematoligst doc, thinks i should try it again.

    any info on experiences with these med.s would be very helpful.

    Hope you all have a good weekend/holiday

  2. FM58

    FM58 New Member

    Not sure of the name of the meds you are referring to. Please check the spelling, as many meds sound & are spelled quite similarly. Perhaps you mean - Niacin (no script needed, it's B3) & Neurontin?

    Confused about "dry kidneys". If you have blood in your urine, you should be treated w/ antibiotics. Please see a urologist. Are you having other symptoms? A cystoscopy is really not that bad. Keep yourself very well hydrated until you do see the uro doc.

    Good luck & keep us updated.

  3. TigerLilea

    TigerLilea Active Member

    There's no such medical term as "dry kidneys". Did your doctor diagnose this? Blood in the urine could be a bladder infection or kidney stones.

    I've used Niacin before, however, I had to stop using it as I flush really bad from even a low dose. Unfortunately, with me I get worse the longer I use it, whereas most people's body will adjust to it after a few days.

    The Neurontin I passed on as I didn't like the list of possible side-effects. I also didn't agree with the doctor that I needed it for sinus pain. It seemed rather extreme.
  4. ulala

    ulala New Member

    can be from kidney stones, among other things.

    You can take no-flush niacin or niacinamide. I don't like naicin because of the flushing feeling I get, but I like niacinamide and thanks for reminding me I need to buy some more. It is supposed to have anti-inflammatory and anti-anxiety properties.
  5. skeptik2

    skeptik2 Member

    Niacin time-released from Walmarts; I've never had a 'flush' from it.
    It brought my cholesterol down about 25 points in 3 months. I take
    100mg in a.m. and again at bedtime. Love it!

    I've taken Neurontin (gabapentin) for years; I was told to start the
    dosage at night for 3 days, then add the next dose in on the 4th
    morning. Now I take an enormous amount for neuropathy in my
    ankles and legs caused by an anesthetic for TMJ surgery way back
    in 1989. I have some dizziness I think if from it, but it is a real
    godsend for my FM and neuropathic pain.

    hope you find what helps you...

  6. Bruin63

    Bruin63 Member

    This is the info i found on the web, and right now i do not want to risk taking it till i find out why i have blood in the urine.

    i will ask my friendly pharmacist, she's pretty cool about helping me, with my meds, and the bad reactions some give me.
    Niaspan ER Chemical Information

    niacin - A water-soluble vitamin belonging to the vitamin B family, which occurs in many animal and plant tissues, with antihyperlipidemic activity.

    Niacin is converted to its active form niacinamide, which is a component of the coenzymes nicotinamide adenine dinucleotide (NAD) and its phosphate form, NADP.

    These coenzymes play an important role in tissue respiration and in glycogen, lipid, amino acid, protein, and purine metabolism. Although the exact mechanism of action by which niacin lowers cholesterol is not fully understood, it may act by inhibiting the synthesis of very low density lipoproteins (VLDL), inhibiting the release of free fatty acids from adipose tissue, increasing lipoprotein lipase activity, and reducing the hepatic synthesis of VLDL-C and LDL-C.

    just to many side effects listed, that i do get from other meds.

    thanks for replying .

    the other med is gabapentin, and i didnt do well on it before, but i may try that one now,

    i am having the bladder test, in oct.
    i already had a ct whiched showed nothing, like tumors or stones,
    this has been going on for a long time, and i have had other tests to rule out other conditions.

    i keep forgetting that not all new symptoms, are from fibro, but may be a new co-exisiting conditions

    thanks again for answering my questions,
    i type mostly in sm caps as i have digital cysts on most of my fingers.


  7. Bruin63

    Bruin63 Member

    She did say, that my kidneys were dry, then she said that i was dehydrated.
    sometimes we do get things mixed up, ;o)

    I can also be the cause of the Blood in my urine, i found a lot of info over the weekend and i may just have a cyst, as i am prone to them.

    i did try the new med, but when my face turned red, and the itchness wasn't stopped by my vistril, i said forget it.

    this is some info i found in case anyone is interested.

    it's from the webmed site. but if you google in kidneys, you will find a ton of info.
    better than going to the library.

    have a great day.


    What is dehydration?

    The majority of the body is made up of water, with up to 75% of the body's weight due to H2O. Most of the water is found within the cells of the body (intracellular space). The rest is found in the so-called extracellular space, which consists of the blood vessels (intravascular space) and the spaces between cells (interstitial space).

    Total body water = intracellular space + intravascular space + interstitial space

    Dehydration occurs when the amount of water leaving the body is greater than the amount being taken in. The body is very dynamic and always changing. This is especially true with water in the body. We lose water routinely when we:


    as humidified air leaves the body,

    when we sweat to cool the body, and

    when we urinate or have a bowel movement to rid the body of waste products.
    In a normal day, a person has to drink a significant amount of water to replace this routine loss.

    If intravascular (within the blood vessels) water is lost, the body can compensate somewhat by shifting water from cells into the blood vessels, but this is a very short-term solution. Signs and symptoms of dehydration will occur quickly if the water is not replenished.

    The body is able to monitor the amount of fluid it needs to function. The thirst mechanism signals the body to drink water when the body is dry. As well, hormones like anti-diuretic hormone (ADH) work with the kidney to limit the amount of water lost in the urine when the body needs to conserve water.

    What causes dehydration?

    Dehydration occurs because there is too much water lost, not enough water taken in, or most often a combination of the two.

    Diarrhea: Diarrhea is the most common reason a person loses excess water. A significant amount of water can be lost with each bowel movement. Worldwide, more than four million children die each year because of dehydration from diarrhea.

    Vomiting: Vomiting can also be a cause of fluid loss; as well, it makes it difficult to replace water by drinking it.

    Sweat: The body can lose significant amounts of water when it tries to cool itself by sweating. Whether the body is hot because of the environment (for example, working in a warm environment), intense exercising in a hot environment, or because a fever is present due to an infection, the body uses a significant amount of water in the form of sweat to cool itself. Depending upon weather conditions, a brisk walk will generate up to 16 ounces of sweat (a pound of water).

    Diabetes: In people with diabetes, elevated blood sugar levels cause sugar to spill into the urine and water then follows. Significant dehydration can occur. For this reason, frequent urination and excessive thirst are among the symptoms of diabetes.

    Burns: Burn victims become dehydrated because water seeps into the damaged skin. Other inflammatory diseases of the skin are also associated with fluid loss.

    Inability to drink fluids: The inability to drink adequately is the other potential cause of dehydration. Whether it is the lack of availability of water or the lack of strength to drink adequate amounts, this, coupled with routine or extraordinary water losses, can compound the degree of dehydration.

    What are the signs and symptoms of dehydration?

    The body's initial responses to dehydration are:

    thirst to increase water intake along with

    decreased urine output to try to conserve water. The urine will become concentrated and more yellow in color.
    As the level of water loss increases, more symptoms can become apparent. The following are further signs and symptoms of dehydration:

    dry mouth

    the eyes stop making tears

    sweating may stop

    muscle cramps

    nausea and vomiting

    lightheadedness (especially when standing).
    The body tries to maintain cardiac output (the amount of blood that is pumped by the heart to the body); and if the amount of fluid in the intravascular space is decreased, the body has to increase the heart rate, which causes blood vessels to constrict to maintain blood pressure. This coping mechanism begins to fail as the level of dehydration increases.

    With severe dehydration, confusion and weakness will occur as the brain and other body organs receive less blood. Finally, coma and organ failure will occur if the dehydration remains untreated.

    How is dehydration diagnosed?

    Dehydration is often a clinical diagnosis. Aside from diagnosing the reason for dehydration, the healthcare provider's examination of the patient will assess the level of dehydration. Initial evaluations may include:

    Mental status tests to evaluate whether the patient is awake, alert, and oriented.

    Vital signs may include postural readings (blood pressure and pulse rate are taken lying down and standing). With dehydration, the pulse rate may increase and the blood pressure may drop because the intravascular space is depleted of water.
    Special consideration: Many people are prescribed high blood pressure medications called beta blockers that may prevent these compensatory increases in the heart rate.

    Temperature may be measured to assess fever.

    Skin will be checked to see if sweat is present and to assess the degree of elasticity (turgor). As dehydration progresses, the skin loses its water content and becomes less elastic.

    Infants may have additional evaluations done, including checking for a soft spot on the skull (sunken fontanelle), assessing the suck mechanism, muscle tone, or loss of sweat in the armpits and groin. All are signs of potential significant dehydration.

    Pediatric patients are often weighed during routine child visits, thus a body weight measurement may be helpful in assessing how much water has been lost with the acute illness.
    Laboratory testing

    The purpose of blood tests is to assess potential electrolyte abnormalities (especially sodium levels) associated with the dehydration. Tests may or may not be done on the patient depending upon the underlying cause of dehydration, the severity of illness, and the healthcare provider's assessment of their needs.

    Urinalysis may be done to determine urine concentration - the more concentrated the urine, the more dehydrated the patient.

    How is dehydration treated?

    As is often the case in medicine, prevention is the important first step in the treatment of dehydration. (Please see the home treatment and prevention sections.)

    Fluid replacement is the treatment for dehydration. This may be attempted by replacing fluid by mouth, but if this fails, intravenous fluid (IV) may be required. Should oral rehydration be attempted, frequent small amounts of clear fluids should be used.

    Clear fluids include:


    clear broths,


    Jell-O, and

    other replacement fluids that may contain electrolytes (Pedialyte, Gatorade, Powerade, etc.)
    Decisions about the use of intravenous fluids depend upon the healthcare provider's assessment of the extent of dehydration and the ability for the patient to recover from the underlying cause.

    The success of the rehydration therapy can be monitored by urine output. When the body is dry, the kidneys try to hold on to as much fluid as possible, urine output is decreased, and the urine itself is concentrated. As treatment occurs, the kidneys sense the increased fluid and urine output increases.

    Medications may be used to treat underlying illnesses and to control fever, vomiting, or diarrhea.

    Can I treat dehydration at home?

    Dehydration occurs over time. If it can be recognized in its earliest stages, and if its cause can be addressed, then home treatment may be adequate.

    Steps a person can take at home to prevent severe dehydration include:

    Patients with vomiting and diarrhea can try to alter their diet and use medications to control symptoms to minimize water loss.

    Acetaminophen or ibuprofen may be used to control fever.

    Fluid replacements may be attempted by replacing fluid by mouth with frequent small amounts of clear fluids (see clear fluids information in previous section).
    If the patient becomes confused or lethargic; if there is persistent, uncontrolled fever, vomiting, or diarrhea; or if there are any other specific concerns, then medical care should be accessed.

    EMS or 911 should be activated for any patient with altered mental status - confusion, lethargy, or coma.

    What are the complications of dehydration?

    Complications of dehydration may occur because of the dehydration and because of the underlying disease or situation that cause the fluid loss.

    Kidney failure

    Kidney failure is a common occurrence, although if it is due to dehydration and is treated early, it is often reversible. As dehydration progresses, the volume of fluid in the intravascular space decreases, and blood pressure may fall. This can decrease blood flow to vital organs like the kidneys, and like any organ with a decreased blood flow; it has the potential to fail to do its job.


    Decreased blood supply to the brain may cause confusion and even coma. If enough organs begin to malfunction, the body itself may fail, and death can occur.


    When the fluid loss overwhelms the body's ability to compensate, blood pressure falls (hypotension) and the patient may go into shock, in which organs in the body may not get enough oxygen to function and thus fail.

    Heat-related illnesses and associated complications

    In heat-related illness, the body's attempt to cool itself by sweating may cause dehydration to the point that muscles may go into spasm (heat cramps). It is often the muscles that are being stressed that will spasm (for example, in people who work outside in a hot environment, ,arm and leg muscles may spasm from lifting and moving heavy objects or equipment; in athletes, leg muscles may fail from running). As fluid loss increases, the patient may be so dehydrated that there is not enough water to sweat and heat exhaustion or heat stroke may occur. Heat stroke is a true medical emergency and 911 or the Emergency Response System should be activated immediately in this situation.

    Electrolyte abnormalities

    In dehydration, electrolyte abnormalities may occur since important chemicals (like sodium and potassium) are lost from the body through sweat. For example, patients with profuse diarrhea or vomiting may lose significant amounts of potassium, causing muscle weakness and heart rhythm disturbances. The health care provider needs to be aware of the fluid and electrolyte balance in the dehydrated patient and be certain to monitor electrolyte levels as rehydration occurs. Some examples of symptoms caused by abnormal electrolyte levels include muscle weakness due to low potassium, heart rhythm disturbances due to either low or high potassium, and seizures due to low sodium.

    It is reasonable to remember that dehydration does not occur quickly, and sometimes it may take hours to slowly correct the fluid deficit and allow the electrolytes to redistribute themselves appropriately in the different spaces in the body. If rehydration is done too slowly, the patient may remain hypotensive and in shock for too long. If done too quickly, water and electrolyte concentrations within organ cells can be negatively affected, causing cells to swell and eventually die.

    Can dehydration be prevented?

    Environment: Dehydration due to the weather is a preventable condition. If possible, activities should not be scheduled in the heat of the day. If they are, adequate fluids should be available and people should be monitored to make certain they are safe.
    Those working in hot environments need to take care to rehydrate often.

    Exercise: People exercising in a hot environment need to drink adequate amounts of water.

    Age: The young and elderly are most at risk. During heat waves, attempts should be made to check on the elderly in their homes. During the Chicago heat wave of 1995, more than 600 people died in their homes.

    Heat related conditions: Know the signs and symptoms of heat cramps, heat rash, heat exhaustion, and heat stroke. Preventing dehydration is one step to avoid these conditions.

    Dehydration at A Glance

    The body needs water to function.

    Dehydration occurs when water intake is less than water loss.

    Symptoms range from mild to life-threatening.

    Prevention is the important first step in treating dehydration.

    The young and the elderly are especially susceptible to dehydration.

    [This Message was Edited on 09/08/2009]
    [This Message was Edited on 09/08/2009]

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