I have been in such a flare and I am trying to get myself out of it. I'm off Neurontin and trying Lyrica now. I'm hoping to lose the weight I gained on Neurontin....but I don't know if Lyrica is any better in that dept. I am interested to know if fatigue increased for others on Lyrica, because mine's been off the charts all week. Hard to know if it's the medication or the flare that's causing it, but I have a lot of swelling and joint pain too. I'd be interested to hear anyone's experience on Lyrica and if it helped or made you worse.