Epstein-Barr Virus Associated Large B-Cell Cardiac Lymphoma

Discussion in 'Fibromyalgia Main Forum' started by ulala, Nov 29, 2008.

  1. ulala

    ulala New Member

    With Simultaneous Manifestation...
    Qedra et al. J Clin Oncol.2008; 26: 5301-5303

    Can anyone access this article? It involves a subscription which I don't have. Thanks!
  2. ladybugmandy

    ladybugmandy Member

    ugh. if i hear of another disease associated with EBV i am gonna scream. so far we have CFS, FM, cervical cancer, lymphoma, breast cancer, gastric cancer, lupus, MS, vitiligo, etc etc etc. it seems like the list goes on and on.

    and since my immune system has already demonstrated incompetence with EBV, i wonder which one of these diseases i am in for.
  3. mindblower

    mindblower New Member

    that seems to be the only chronic disease truly found associated with EBV and it predominantly occurs in central African children who seem were already genuinely-seriously immunocompromised, very much unlike anything ever found in those of us with ME/CFS.


    Tests demonstrating mere exposure to EBV, latency and even some activation of it in one's system is very common globally, even those just having hang nails and very great well-being show these sort of results on tests. It remains speculative and extremely unlikely at this point that this virus has any real causal link to a huge litany of illnesses one may get over the course of a life time, let alone ME/CFS.


  4. star273

    star273 New Member

    My husband suffered from nasel pharengial carcinoma in his sinuses 9 years ago. They said it was caused from getting the Epstein Barr Virus at some point. I was also tested for it and tested positive. They believe one of us gave it to the other. So yes, I do know that cancer can be linked to EBV. I am sure it also has to do with FM. I was tested for EBV when I found out I had FM..... Crazy, I know. I think there are many viruses linked to many things...
    That is why I think it is SO IMPORTANT to keep our immune system as good as we can..... supplements, some form of exercise (whatever your body can handle), eating right, whatever we can do to keep our immune systems good. [This Message was Edited on 11/30/2008]
  5. mindblower

    mindblower New Member

    NPC is also a very rare cancer and seems to have similar geographical predisposition to Burkitt's when associated with EBV, which is interesting. BUT in the even rarer cases of the type of it found in the very few from the west who come down with it, EBV seems to NOT be linked to it.

    Your husband's docs may have overlooked this point:


    Also, our immune systems in the developed world are fairly robust on average most of the time, contrary to what some suggest and despite some less than ideal health habits that are common to us here.

    [This Message was Edited on 11/30/2008]
  6. ladybugmandy

    ladybugmandy Member

    i understand that you are a skeptic and thats fine, but saying EBV has not conclusively been linked to cancers is ridiculous.

    and..seriousy...i am not going to trust the NIH or CBC to give me any 'real' info.
  7. mindblower

    mindblower New Member

    "...saying EBV has not conclusively been linked to cancers is ridiculous..."

    It's actually ridiculous to conclusively say EBV is causal to anything except the few illnesses evidence supports it potentially causes, like these rare African epicentered cancers that I did acknowledge. But these cancers are rare and even in such cases other predisposing factors if addressed may have prevented them despite the presence of any EBV.

    This is not skepticism, just distinguishing fact from theory and what theories available facts tend to support. I'm not attacking you, but are you sure you're not confusing facts about EBV with weakly supported theories about it?


    [This Message was Edited on 12/01/2008]
  8. ladybugmandy

    ladybugmandy Member

    when you say predisposing factors, do you mean genes? ...because one can say "defective genes" are the cause of everything. its not saying much.
  9. star273

    star273 New Member

    I agree with you ladybug!!! You may not mean to be attacking us MB but I do think that any kind of cancer can be realted to a virus. We had several Dr's tell us it was related to EBV. We were also told that it is most common in Asia. We had some of the best Dr's. I have done research myself and found that it can be related. To give credit to both sides. I understand what your saying MB but to some of us who have been told by many Dr's and done much research, I think you should understand our point too. I also dont think we are here to critisize each other, but to encourage.............
    [This Message was Edited on 12/01/2008]
  10. star273

    star273 New Member

    Are you in the medical profession??? Just curious???
  11. mindblower

    mindblower New Member

    "Are you in the medical profession???..."

    No. I just happen to understand why most of them and most ME/CFS doc specialists, especially, don't see this condition as caused by any infection, viral or otherwise.

    The better evidence supports their view by far.


    [This Message was Edited on 12/01/2008]
  12. mindblower

    mindblower New Member

    "when you say predisposing factors, do you mean genes?..."

    For these rare African/Asian cancers, I was mostly thinking along the lines of chronic malnutrition. Burkitt's I've read occurs in poor kids in these countries, not adults nor kids from better environments.

    I was also thinking of a study here in the U.S. that showed two towns of equal demographics; population number, wealth, gender, ages, ethnic representation. Both towns being on opposite sides of the country, two totally different states, was the only obvious difference.

    One had a peak colon cancer occurrance of this one type of colon cancer 15 years earlier on average compared to the other town. Long story short, researchers concluded it wasn't genes, viruses or many things commonly thought might account for this strange difference in age onset for this one cancer.

    It was local soil. As I recall, one town's source of routine staple foods(bread I think mostly) were grown in /made from local soil with much lower folate levels by comparison.

    This was the town with the clearly significant younger age development of this cancer.

    [This Message was Edited on 12/01/2008]
  13. ladybugmandy

    ladybugmandy Member

    CFS is caused by infection. the glandular aches, the anemia, the low vitamin D, the onset immediately after infection...COME ON. its common sense.

    we just havent determined the exact pathogens in everyone or why they have become chronic. its genetic and its infection.

    a gene expressed during viral infection was found...ampligen helps...its INFECTION.

    you will see.
    [This Message was Edited on 12/01/2008]
  14. mindblower

    mindblower New Member

    "CFS is caused by infection. the glandular aches, the anemia, the low vitamin D, the onset immediately after infection...COME ON. its common sense..."

    Common sense often isn't! We've also already had this conversation here recently, re-read my posts if you somehow missed some.

    You LOST that argument as I recall. ;) And you now want to site Ampligen's record with ME/CFS?

    OMG! I've covered this already too, it's not great barring some public image makeover capacity.


    [This Message was Edited on 12/01/2008]
  15. ladybugmandy

    ladybugmandy Member

    my brain fog is horrible and i cannot remember much. i have to wonder if you have CFS.

    there is a fine line between being a skeptic and trying to dash everyone's hopes. you keep crossing the line.
  16. mindblower

    mindblower New Member

    Got it about your brain fog. Maybe you should review my recent posts and/or take a breather, only post respond when feeling more clear?

    And, yes, I have ME/CFS. I have no doubt now and this has been confirmed by several docs over the years, including Dr Cheney and Dr Goldstein, if you prefer familiar names.

    My overt symptom onset started with "mono", same as you as I recall(look over my profile for more detail). And as far as "trying to dash everyone's hopes", this is a reaction I sometimes get that really is not about me and much more about where the person reading my comments is at in their understanding of ME/CFS.

    I often get the sense that many ME/CFS community members incorrectly confuse the idea of causal infection with opportunistic infections or activations. I think the latter, which definitely occur in many of us, are responsible for much of why some people misunderstand what I and some others on this board are saying about this condition.

    As has been said, half of solving a problem is about accurately defining what the problem is in the first place. Failing to do this can have a profound cost in time, money, energy, and life opportunities, including total loss of life(death) in some instances.

    MB[This Message was Edited on 12/02/2008]
  17. star273

    star273 New Member

    When I read different posts in here, I sometimes wonder why people are being so rude. I dont really think we are here for that.... If we wanted that, we could go somewhere else. I have never posted anything back to "those rude people", I usually just think how sad it is that, that person must be so miserable that they have nothing nice to say, but in your case, as ladybug said, you are crossing the line.... all you have done is mock us and you seem to have an answer for everything..... we all do what we can with what we have, so maybe you should think of others when posting your comments.
  18. bct

    bct Active Member

    MB is not being rude or disrespectful. I, for one, greatly appreciate MB's posts, and send him my thanks.

    Regards to all,
  19. winsomme

    winsomme New Member

    i think it is important to work hard to make these theoretical discussions about the research and the researchers and not each other...I certainly am making an effort to do better at that...

    and on that count, there are currently talented and respected DRs and researchers that believe that chronic infection could be a major component of the pathophysiology of CFS.

    if some PWCs agree with those particular researchers or DRs, it doesn't necessarily say anything about their own personal understanding of CFS. They are simply supporting the sentiments of someone who if nothing else is an expert and possessing a robust understanding of the condition and has a particular viewpoint...

    very smart people disagree about the role of chronic infection in CFS. it doesn't mean that certain researchers are less informed, they simply have a different assessment of the topic.

    the question of whether infection is an open area of investigation in CFS is certainly confirmed by the fact that the Whittemore Inst - one of the labs looking at CFS - is still looking there. the level of interest in this area will vary from researcher to researcher, but the question certainly is an open one and being actively pursued.

    as it is, might i add, in other poorly understood conditions like MS and (getting back to the OP) Lymphoma.
    [This Message was Edited on 12/02/2008]
  20. findmind

    findmind New Member

    Thank you winsomme, for getting this conversation back off the "The View" page, with everybody sniping at one another.

    Mindblower and ladybug, I can see both of your points of view regarding what "causes" ME/CFS; however, I really cannot see any justification for the inappropriate tone. From the posts, you two have been at it before, right? That's ok; but why don't you two just argue with each other in a chat room, and try to keep it neutral here?

    Since the board is visited by more and more people now, it really is incumbant upon us to make sure we do not sound like other boards, that we are civil and even giving in our discussions, always showing the other posters our respect and caring.

    WE will not "discover" the reason(s)for our ME/CFS, that's for sure. The science will tell us eventually, and that hope keeps me going, and coming here, to share our hopes, fears, and decisions as to how to treat ourselves and our symptoms.

    Respect is so important among us, as we have found so little "out there".

    Much respect, caring and huggies to you all...