Hi Everyone! Thanks for all the kind words and advice and positive feedback you have shared with my husband. It is all so helpful and he has been very helpful as well. I am 49 years old and haven't felt right for a very long time and it bothers me so much to have to cut back on things I enjoy doing. I was diagnosed with Grave's Disease a few years ago and that has also interrupted my generally healthy life. I did the Radio Active Iodine treatment and it took a while to get the right dosage of synthoid to get me out of hypo land but all is great there.. As of this time, I am on 60 mg. of Lexapro for depression and my thyroid meds as well as meds for Cholesterol which have worked beautifully so now I am in the normal range! My doc has decided to try me on Cymbalta which I will be doing in the next week so I will be comming off of the Lexapro slowly and adding that. Celexa did nothing for the pain. I feel like an Advil addict! He has given me Ultram ER 200 mg. per day AFTER 2 weeks on the cymbalta so as not to confuse me as far as side effects. I'd be greatful to hear from someone on these meds and their experiences if you want to share. I'm somewhat nervous about beginning new drugs. Thank you again and I'm looking forward to contributing what I can and sharing! Have a great night!