Exercise and cognitive performance in CFS

Discussion in 'Fibromyalgia Main Forum' started by tansy, Sep 26, 2005.

  1. tansy

    tansy New Member

    Exercise and Cognitive Performance in Chronic Fatigue Syndrome.

    Journal: Med Sci Sports Exerc. 2005 Sep;37(9):1460-1467.

    Cook DB [1,3], Nagelkirk PR [4], Peckerman A [2], Poluri A [2], Mores J
    [2], Natelson BH [1,3].

    [1] University of Wisconsin-Madison, Department of Kinesiology; [2]
    University of Medicine and Dentistry of New Jersey-New Jersey Medical
    School, CFS Cooperative Research Center, Newark, NJ; [3] University of
    Medicine and Dentistry of New Jersey-New Jersey Medical School, Department
    of Neurosciences, Newark, NJ; and [4] Michigan State University, Lansing, MI.

    NLM Citation: PMID: 16177595


    PURPOSE: To determine the effect of submaximal steady-state exercise on
    cognitive performance in patients with chronic fatigue syndrome (CFS)
    alone, CFS with comorbid fibromyalgia FM (CFS+FM), and sedentary healthy
    controls (CON).

    METHODS: Twenty CFS-only patients, 19 CFS+FM, and 26 CON completed a
    battery of cognitive tests designed to assess speed of information
    processing, variability, and efficiency. Tests were performed at baseline,
    immediately before, and twice following 25 min of either cycle ergometry
    set at 40% of peak oxygen capacity or quiet rest.

    RESULTS: There were no group differences in average percentage of peak
    oxygen consumption during exercise (CFS = 45%; CFS+FM = 47%; Control = 43%:
    P = 0.2). There were no significant effects of acute exercise on cognitive
    performance for any group. At baseline, one-way ANOVA indicated that CFS
    patients displayed deficits in speed of processing, performance
    variability, and task efficiency during several cognitive tests compared
    with healthy controls. However, the CFS+FM patients were not different than
    controls. Repeated measures ANOVA indicated that across all tests (pre- and
    postexercise) CFS, but not CFS+FM, were significantly less consistent
    (F2,59 = 3.7, P = 0.03) and less efficient (F2,59 = 4.6, P = 0.01) than
    controls.

    CONCLUSION: CFS patients without comorbid FM exhibit subtle cognitive
    deficits in terms of speed, consistency, and efficiency that are not
    improved or exacerbated by light exercise. Importantly, our data suggest
    that CFS+FM patients do not exhibit cognitive deficits either pre- or
    postexercise. These results highlight the importance of disease
    heterogeneity in studies determining acute exercise and cognitive function
    in CFS.