Exercise causes increase in bacterial translocation in CFS that parallels PEM

Discussion in 'News and Research' started by ljimbo42, Mar 7, 2016.

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  1. ljimbo42

    ljimbo42 Active Member

    Changes in Gut and Plasma Microbiome following Exercise Challenge in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS).
    This study was published on December 18, 2015.

    What I found most interesting about this study is that the highest levels of bacterial translocation (lipopolysaccharides etc.) was 2 days after the exercise challenge. Which usually coincides with the peak of post exertional malaise (PEM) for people with cfs/me! Lipopolysaccharides cause a strong immune reaction with flu-like symptoms, just like those experienced in cfs/me.

    Here is a link to the abstract-

    Here is a link to the full paper-

    TigerLilea likes this.
  2. Mikie

    Mikie Moderator


    Thank you so much for sharing this. I'll check it out. Exercise only serves to make me more exhausted. I do it for my heart health but I pay a price for it.

    Love, Mikie
  3. TigerLilea

    TigerLilea Active Member

    Mikie, exercise also makes me more exhausted, also, but like you I want to keep my heart and body healthy so that I go into old age being able to take care of myself. It hasn't helped my CFS to take it easy and rest or pace, so when I have the energy I go for it, and on the days that I don't, I do less.
  4. Mikie

    Mikie Moderator

    Hi, TigerLilea,

    Yes, I also have to pace myself. I'm in a flare, likely triggered by our Red Tide and, more recently, slash pine pollen. It's always something with us. Good to see you posting. I'm laughing at your tag line about CFS/ME and Menopause--so true, so true!

    Love, Mikie
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