Discussion in 'Fibromyalgia Main Forum' started by luigi21, Mar 4, 2013.
pretty good findings actually and I am glad they focused on the peripheral and soft tissue abnormalities that many don't and I am not sure why as I believe it is the peripheral dysfunction that is affecting the CNS (ie. sensitization).
you can also add low ATP (backed by studies) in the muscles of those with FM. There is clearly dysfunction in our muscles and I would argue connective tissue as well (ie. facia and tendons)
But boy that is a LOT of abnormalities (and that list is not even comprehensive) yet some people and doctors (more so old farts) still don't believe we are that ill - just shameful.
It is fairly clear that FM is a poorly diagnosable condition like ME/CFS. Hence the "old fart MD's).
Over 48% of people with ME/CFS fit the (US Rheumatological Assoc.) criteria for FM.
All the items in the list by FM Network are all items of ME/CFS.
In people with ME/CFS and FM the best studies have been done on the immune system and those abnormalities can explain ALL other signs, such as fibrous tissue stiffening, low blood flow, autonomic abnormalities, brain fMRI findings and gut problems.
While trans-cortical electro-stimulation does help to cut pain it does nothing for the other symptoms. It also interesting to hear people's descriptions of their symptoms. Mostly they do not fit with the hypothesis that Fm is "just" a sensitivity problem (autonomic). This sensitivity theory denies fibrous tissue origins of pain, whereas the evidence suggests that local immune abnormalities induce homeostatic imbalances in the vascular and fibrous tissues which generate pain.
I have done studies on pain in FM people and to say they are "hypersensitive" to pain is not correct. They have normal sensitivity to mechanically induced pain. This contradicts the "sensitivity" theory. I also take issue with those studies who have found that people with FM have hypersensitivity to thermally induced pain. We have not found that, although some FM people do have but even normals can have hypersensitivity to thermal pain depending on circumstances and I have never found a study properly controlling the extraneous variables.
Those people with "FM" who do not fit the criteria for ME/CFS may be a different group with similar symptoms but which can be explained by other pathologies, such as hypothyroidism, Multiple sclerosis, SLE, small fiber neuropathy, multiple spinal stenosis etc.
It is an error to think that FM is a "single" disease or even a disease at all. It is however a serious set of symptoms of an underlying disease process, which will vary from case to case. So any doctor who says Fm doesn't exist is partly correct but should then be working to find the underlying pathologies not tossing FM into a psychological basket as some do. It is my thinking that people with FM should be always re-classified as to their underlying disease. Otherwise they will be put on pain killers and left to fight their pain over many years.
[This Message was Edited on 03/04/2013]
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