Firecop1066: Igenex Lyme results

Discussion in 'Fibromyalgia Main Forum' started by Juloo, Feb 1, 2006.

  1. Juloo

    Juloo Member

    Thanks for posting the links to all the information that you did. I read it all and printed it out so that I can read and understand it.

    I received my printed results today. Although I do not fit the Igenex or CDC 'strict' definition of positive, there was more listed than I thought. I looked up all the bands so I could know what the antibodies were to.

    IGG (all kDa)
    18 +
    31 IND
    41 +
    58 ++
    66 +

    IGM (all kDa)
    18 +
    23-25 IND
    31 IND
    39 IND
    41 IND

    all other bands Negative.
  2. Juloo

    Juloo Member

    Bumping for Firecop1066
  3. Juloo

    Juloo Member

    With everything you've posted, you've already increased my Lyme knowledge by about 1000%. The good wishes are appreciated as well. Here's to the first step on the road back from Lyme...
  4. redsox10

    redsox10 New Member

    Dr. Jones is a well beloved Lyme pediatrician in Connecticut. He has
    treated thousands of children for Lyme disease. Here is his take on
    western blots:
    Charles Ray Jones, M.D.

    Addendum Regarding Lyme Serology

    There are nine known [Lyme] Borrelia burgdorferi Genus species specific
    KDA Western Blot antibodies (bands): 18, 23, 31, 34, 37, 39, 83 and 93.

    Only one of these Borrelia burgdorferi genus specific bands is needed to
    confirm that there is serological evidence of exposure to the Borrelia
    burgdorferi spirochete and can confirm a clinical diagnosis of Lyme Disease.

    CDC Western Blot IgM surveillance criteria includes only two burgdorferi
    genus species specific antibodies for IgM 23 and 39 and excludes the
    other seven Borrelia burgdorferi antibodies.

    CDC Western Blot IgG surveillance criteria includes 18, 23, 30, 37, 39
    and 93 and excludes bands 31, 34 and 83.

    It does not make sense to exclude any Borrelia burgdorferi genus
    species-specific antibodies in a Lyme Western Blot, and to include only
    two of these antibodies in IgM because all the antibodies in IgG were
    once IgM.

    IgM converts to IgG in about two months unless there is a persisting
    infection driving a persisting IgM reaction. This is the case with any
    infection including a Borrelia burgdorferi induced Lyme disease.

    The CDC wrongfully includes five non-specific cross-reacting antibodies
    in its Western Blot surveillance criteria: 28, 41, 45, 58 and 66. This
    leads to the possibility of false positive Lyme Western Blots. There can
    be no false positives if only Borrelia burgdorferi genus
    species-specific antibodies are considered. One can have a CDC
    surveillance positive IgG Lyme Western Blot with the five non-specific
    antibodies without having any Borrelia burgdorferi genus species
    specific antibodies.

    This does not make sense.

    The CDC recommends that the Lyme Western Blot be performed only if there
    is a positive or equivocal Lyme ELISA. In my practice of over 6000
    children with Lyme disease, 30% with a CDC positive Lyme Western Blot
    have negative ELISA's. The Lyme ELISA is a poor screening test. An
    adequate screening test should have false positives, not false negatives.

    Rev. 2/25/04

  5. pawprints

    pawprints New Member

    It seems many patients going to the FFC are now testing positive for Lyme disease. It may not be the CDC definition of Lyme, but there is enough evidence to suggest Lyme. Is it possible that Lyme is the new CFIDS?
  6. pawprints

    pawprints New Member

    So that would apply even if just one band specific to Borrellia was positive on the IGG or was IND?
    [This Message was Edited on 02/02/2006]
  7. redsox10

    redsox10 New Member

    That is correct. One band specific to Borrellia would be evidence of exposure to the Borrelia. My daughter has many positive bands but my son only had band 39. He did show positve to babesia on PCR testing. He is diagnosed with Lyme Disease with Babesia and is responding to treatment.

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